Developmental competence is the ability to differentiate in response to an appropriate stimulus, as first elaborated by Waddington in relation to organs and tissues. Competence thresholds operate at all levels of biological systems from the molecular (e.g. the cell cycle) to the ontological (e.g. metamorphosis and reproduction). Reproductive competence, an organismal process, is well studied in...

The cellular slime mold Dictyostelium discoideum undergoes a transition from single-celled amoebae to a multicellular organism as a natural part of its life cycle. A method of cell-cell signaling that controls chemotaxis, morphogenesis, and gene expression has developed in this organism, and a detailed understanding of this signaling system provides clues to mechanisms of intercellular communic...

Adaptive phenotypic plasticity in life history traits, behaviours, and strategies is ubiquitous in biological systems. It is driven by variation in selection pressures across environmental gradients and operates under constraints imposed by trade-offs. Phenotypic plasticity has been thoroughly documented for multicellular taxa, such as insects, birds and mammals, and in many cases the underlyin...

During the evolution of multicellular organisms, the unit of selection and adaptation, the individual, changes from the single cell to the multicellular group. To become individuals, groups must evolve a group life cycle in which groups reproduce other groups. Investigations into the origin of group reproduction have faced a chicken-and-egg problem: traits related to reproduction at the group l...

Three recent books on the evolutionary biology of aging and sexual reproduction are reviewed, with particular attention focused on the provocative suggestion by Bernstein and Bernstein (1991) that senescence and genetic recombination are related epiphenomena stemming from the universal challenge to life posed by DNA damages and the need for damage repair. Embellishments to these theories on agi...

Quantum and biological systems are seldom discussed together as they seemingly demand opposing conditions. Life is complex, "hot wet" whereas quantum objects small, cold well controlled. Here, we overcome this barrier with a tardigrade -- microscopic multicellular organism known to tolerate extreme physiochemical conditions via latent state of life cryptobiosis. We observe coupling between the ...

This paper expands Mosaic World, an artificial life model, in order to directly test theories on the emergence of multicellular life. Five experiments are conducted and demonstrate that both the presence of predation and accidental aggregation are sufficient conditions for the transition to multicellularity. In addition, it is shown that division of labour is a major benefit for aggregation, an...

The Geozoic encompasses the 3.6 Ga interval in Earth history when life has existed. Over this time, life has diversified from exclusively tiny, single-celled organisms to include large, complex multicellular forms. Just how and why this diversification occurred has been a major area of interest for paleontologists and evolutionary biologists for centuries. Here, we compile data on organism size...