OBJECTIVE To assess the early vascular effects of sunitinib in patients with renal cell carcinoma (RCC) with diffusion-weighted magnetic resonance imaging (DWI), dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and T2* perfusion MRI. PATIENTS AND METHODS In 10 patients with abdominal RCC lesions, DWI, DCE-MRI and T2* perfusion MRI measurements at 3 Tesla were performed at base...

headache for one month. MRI revealed a small expanded nodule in the head of the right caudate nuclei (Fig. 1). It was hyper intense on both T1(left) and T2-weighted (right) images. Bleeding was suspected, however, other causes including tumor could not be excluded at this time. Subsequent angiography showed no abnormality. Her symptom disappeared gradually without any treatment. Four weeks late...

White matter myelination is essential to postnatal neurologic maturation and can be accurately evaluated by magnetic resonance imaging (MRI). Accordingly, MRI pulse sequences should be optimized for detection of myelin in young children. T1-weighted images are most useful during the first year of life. These demonstrate myelin-related white matter hyperintensity consequent to increasing cholest...

Magnetic resonance imaging (MRI) is often divided into structural MRI and functional MRI (fMRI). The former is a widely used imaging technique in research as well as in clinical practice. This review describes the more important developments in structural MRI in recent years, including high resolution imaging, T2 relaxation measurement, T2*-weighted imaging, T1 relaxation measurement, magnetisa...

BACKGROUND Iron-loaded cardiac complication is the essential cause of mortality in patients with thalassemia. Early detection and treatment of cardiac over-load can reduce mortality. OBJECTIVES The current study aimed to evaluate the relationship between serum ferritin levels and T2* magnetic resonance imaging (MRI) of heart and liver and liver iron concentration (LIC) to diagnose iron over l...

CONTEXT While gray matter T2 hypointensity in multiple sclerosis (MS) has been associated with physical disability and clinical course, previous studies have relied on visual magnetic resonance imaging (MRI) assessments. OBJECTIVE To quantitatively determine if T2 hypointensity is associated with conventional MRI and clinical findings in MS. DESIGN Case-control study. SETTING University-a...

Magnetic resonance imaging (MRI) is often divided into structural MRI and functional MRI (fMRI). The former is a widely used imaging technique in research as well as in clinical practice. This review describes the more important developments in structural MRI in recent years, including high resolution imaging, T2 relaxation measurement, T2*-weighted imaging, T1 relaxation measurement, magnetisa...

Background: MRI facilitates early recognition of rheumatoid arthritis (RA) by depicting inflammation. Contrast-enhanced T1-weighted and T2-weighted fat-suppressed sequences have been sensitive thus recommended, but are hampered invasiveness, costs long scan time. Therefore we introduced a modified Dixon-sequence (mDixon) which is more patient-friendly, reduces cost, times 83%. However, it not k...

We studied the utility of pancreatic magnetic resonance imaging (MRI) in 72 thalassemia major patients (21 diabetic, 51 normoglycemic). Diabetic patients were significantly older (p<0.0001) and had smaller pancreas volume (p<0.0001). The two groups were comparable for ferritin and MRI-T2* heart, liver and pancreas. Pancreatic T2* signals were abnormal in 80% of both groups, and correlated with ...