نتایج جستجو برای: mri rat

تعداد نتایج: 379670  

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی تهران 1372

عضله رحم rat از نظر ساب تایپ های رسپتور p1 پورینرژیک مورد بررسی قرارگرفت . به این جهت آدنوزین و آنالوگهای آن مورد بررسی قرار گرفتند . نتایج بدست آمده نشان میدهند که آثار مهاری آدنوزین و آنالوگهایش بر روی دامنه انقباضات الکتریکی رحم rat بواسطه هیچیک از ساب تایپ های a1 و a2 صورت نمیگیرد، بلکه اینکار از طریق ساب تایپ جدیدی از رسپتور p1 انجام میگیرد. ترکیباتی که درموقعیت 5 حلقه ریبوزاستخلاف دارند (...

2014
Peter Bandi Gabor Jakab Norbert Zsoter Domokos Mathe Gabor Nemeth Kalman Nagy Sandor Hobor Laszlo Papp

Department of Software Engineering, Mediso Ltd., Budapest, Hungary The aim of current work was to automatically derive a body-lung-air three-valued material map from MRI images for pre-clinical PET attenuation correction. Our goal was also to measure the effect of attenuation on corresponding pre-clinical PET images. 12 mouse and 9 rat PET/MRI images were acquired by nanoScan PET/MRI (Mediso). ...

2012
A. Daoust E. L. Barbier S. Bohic Alexia DAOUST Emmanuel Luc BARBIER

words count: 242 ABSTRACT Manganese enhanced MRI (MEMRI) offers many possibilities such as tract tracing and functional imaging in vivo. Mn is however neurotoxic and may induce symptoms s of Mn-induced neurotoxicity are not clear. In this study, we combine synchrotron X-ray fluorescence microprobe (SR-XRF) and MEMRI techniques to investigate spatial distribution of Mn within the rat hippocampus...

Journal: :Journal of magnetic resonance imaging : JMRI 2008
Hui Xu Jing-Xia Xie Xuan Li Zheng-Han Yang Zhuo-Zhao Zheng Bin Wang Zheng Wang

PURPOSE To investigate the value of perfusion-weighted MRI in the evaluation of the intranodular hemodynamic characteristics of dysplastic nodules (DNs) and hepatocellular carcinomas (HCCs) in an experimental rat model. MATERIALS AND METHODS A total of 40 rats with chemically-induced DNs and HCCs were investigated. Single-slice gadolinium-enhanced perfusion-weighted MRI was performed to evalu...

Journal: :Magnetic resonance in medicine 2014
Eric R Muir Damon Cardenas Shiliang Huang John Roby Guang Li Timothy Q Duong

PURPOSE Hyperbaric oxygen therapy has shown efficacies in the treatment of a number of diseases. The goal of this study was to develop a rodent hyperbaric chamber for MRI studies and to investigate the effects of hyperbaric air and hyperbaric oxygen on local magnetic field (B0 ) and MRI relaxation parameters in the rat brain. METHODS A hyperbaric chamber, constructed to fit inside an animal M...

2016
Huanling Liu Anna Jablonska Yuguo Li Suyi Cao Dexiang Liu Hanwei Chen Peter CM Van Zijl Jeff W.M. Bulte Miroslaw Janowski Piotr Walczak Guanshu Liu

Citicoline (CDPC) is a natural supplement with well-documented neuroprotective effects in the treatment of neurodegenerative diseases. In the present study, we sought to exploit citicoline as a theranostic agent with its inherent chemical exchange saturation transfer (CEST) MRI signal, which can be directly used as an MRI guidance in the citicoline drug delivery. Our in vitro CEST MRI results s...

Journal: :Magnetic resonance in medicine 2013
S Richardson B Siow A M Batchelor M F Lythgoe D C Alexander

In vivo magnetic resonance imaging (MRI) assessment of neuronal tissue is prone to artifacts such as movement, pulsatile flow, and tissue susceptibility. Furthermore, stable in vivo scans of over 3 h are difficult to achieve, experimental design is therefore limited. Using isolated tissue maintained in a viable physiological state can mitigate many of these in vivo issues. This work describes t...

Journal: :Cardiovascular Diabetology 2006
Rajprasad Loganathan Mehmet Bilgen Baraa Al-Hafez Mohammed D Alenezy Irina V Smirnova

BACKGROUND Diabetes is a major risk factor for cardiovascular disease. In particular, type 1 diabetes compromises the cardiac function of individuals at a relatively early age due to the protracted course of abnormal glucose homeostasis. The functional abnormalities of diabetic myocardium have been attributed to the pathological changes of diabetic cardiomyopathy. METHODS In this study, we us...

Journal: :IEEE Access 2023

An important topic in chemical exchange saturation transfer (CEST)-magnetic resonance imaging (MRI) is that certain CEST effects (such as amide proton effects) require sufficiently long time to reach steady state, which becomes a constraint the clinical application. To address this issue, we develop deep learning-based model predict quasi-steady-state (QUASS) from images with short times obtain...

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