نتایج جستجو برای: moxonidine

تعداد نتایج: 185  

Journal: :Acta poloniae pharmaceutica 2017
Konrad Boblewski Artur Lehmann Aleksandra Marchwinska Anita Kornicka Aleksandra Wasilewska Franciszek Saczewski Apolonia Rybczynska

Since clonidine was introduced in clinical practice, attempts are still made to obtain substances capable of centrally controlling blood pressure, however with pharmacological profile better than currently avail- able, such as moxonidine and rilmenidine. Recently synthesized indazole derivatives exert promising action on blood pressure and heart rate in Wistar rats. In the present study, our ai...

Journal: :Pharmacological reports : PR 2007
Gerhard J Molderings Manfred Göthert Ivar von Kügelgen

The present study aimed at investigating the influence of imidazoline receptor ligands on the proliferation of PC12 cells and the involvement of the sphingosine-1-phosphate (S1P) signaling system in this effect. In cultured PC12 cells, S1P (0.3-100 nM) and the I(1) imidazoline receptor ligands moxonidine (0.3 and 1 mM), agmatine (1 mM), idazoxan (10-100 microM) and efaroxan (1-100 microM) conce...

Journal: :The Journal of Clinical Endocrinology & Metabolism 2017

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