Invasive mould disease is a growing threat for immunocompromised patients. The optimum time to use mould-active antifungal agents is much debated. Current approaches to antifungal prophylaxis, early treatment (empirical and pre-emptive therapy) and treatment of documented mould infections in onco-haematology patients are discussed.

Burn-on and penetration defects in steel casting are principally caused by localised overheating of the sand mould or cores. Such overheating can cause liquid metal to compromise the mould surface and entrain onto the surface of the mould. A method has been developed to predict likely burn-on and penetration defect locations as part of a standard casting simulation. The method relies on determi...

In glass container manufacturing (e.g. production of glass bottles and jars) an important process step is the blowing of the final product. This process is fast and is characterized by large deformations and the interaction of a hot glass fluid that gets into contact with a colder metal, the mould. The objective of this paper is to create a robust finite element model to be used for industrial ...

This article is focused on the optimization of heat radiation intensity across the surface of an aluminium mould. The mould is warmed by infrared heaters located above the mould surface, and in this way artificial leathers in the automotive industry are produced (e.g. the artificial leather on a car dashboard). This described model allows us to specify the location of infrared heaters over the ...

Bamboo timber is very vulnerable to mould fungi, a characteristic that is attributed to the rich sugar, starch, and protein present in bamboo. Solvents including cold water, hot water, benzene/ethanol, ethanol/ether, 1% NaOH, and 1% HCl can dissolve corresponding components from bamboo, which might be helpful to the resistance of bamboo against mould fungi. In order to study the relationship be...

Critical reviews over the past 10 yrs have found increased respiratory and allergic health outcomes for children living in damp and mouldy environments. However, recent studies have suggested that early childhood exposure to specific mould components may actually protect children from developing allergy. We conducted a systematic review of observational studies published in English from January...

A 24 year old man developed severe asthma two years after starting to work in a plywood plant. Four years later the patient had to stop working because of the increasing severity of his asthma. Three months after leaving his job, the patient's asthma was greatly improved. His job consisted of placing plywood sheets into a drying machine. The plywood sheets had stayed outside in wet conditions f...

The official WHO/IUIS database (www.allergen.org) currently lists 77 mould allergens from a variety of protein families. To date, only eight recombinant single allergens from three mould species are available for molecular allergy diagnosis of mould sensitization. These include rAlt a 1, the major allergen in Alternaria alternata-sensitized individuals, and enolase rAlt a 6 with it potential cr...

We construct electronic oscillator from acellular slime mould Physarum polycephalum. The slime mould oscillator is made of two electrodes connected by a protoplasmic tube of the living slime mould. A protoplasmic tube has an average resistance of 3 MOhm. The tube’s resistance is changing over time due to peristaltic contractile activity of the tube. The resistance of the protoplasmic tube oscil...