Genetic variants within the serotonin transporter gene (5-HTTLPR) impact the neurobiology and risk for anxiety-related behaviours. There are also gender differences in the prevalence of anxiety-related behaviours. Although numerous studies have investigated the influence of 5-HTTLPR genotype on the neural systems involved in emotional regulation, none have investigated how these effects are mod...

The study was conducted to evaluate the sexual dimorphism in the morphometric parameters of the whole brain and the brainstem in adult captive African giant pouched rats. Twenty-nine brain samples, comprising 15 females and 14 males, were utilized. Following brain extraction by standard procedures, the mean values of the weights, lengths, diameters, and volumes of the intact brains and the brai...

INTRODUCTION The frequency of different morphological types and extrasulcal (visible) surface area of the cingulate gyrus, were measured and analysed in order to obtain more precise data about morphology, right/left and sex differences in the human brain. MATERIAL AND METHODS The study included 42 brains (84 hemispheres) from persons of both sexes and of different age (26 males, 16 females, 2...

As with previous critiques of voxel-based morphometry (e.g., see Bookstein, 2001, Mehta et al., 2003), Christos Davatzikos (2004) reprises issues that have engaged the functional neuroimaging community for many years. In this instance, the issue is the distinction between multivariate and mass-univariate analyses of imaging data. Put simply, Davatzikos is pointing out that pathology can be expr...

We applied a new method to visualize the three-dimensional profile of sex differences in brain structure based on MRI scans of 100 young adults. We compared 50 men with 50 women, matched for age and other relevant demographics. As predicted, left hemisphere auditory and language-related regions were proportionally expanded in women versus men, suggesting a possible structural basis for the wide...