Background and objectives: Gastroesophageal reflux is a common chronic disease that impairs individuals’ quality of life, wherein patients should receive prolonged, and sometimes lifelong, treatment with chemical drugs, that in addition to high costs they can lead to side effects in the long term .Hawthorn fruit is one of the drugs used in traditional medicine to relieve reflux symptoms and to ...

CONTEXT Gastroesophageal reflux disease is a chronic disease in which gastroduodenal contents reflux into the esophagus. The clinical picture of gastroesophageal reflux disease is usually composed by heartburn and regurgitation (typical manifestations). Atypical manifestations (vocal disturbances and asthma) may also be complaint. OBJECTIVE To analyse the clinical, endoscopic, manometric and ...

BACKGROUND AND OBJECTIVES Adult laparoscopic Nissen fundoplication has been steadily growing since its introduction to the United States in the 1990s. Its advantage over the traditional open approach is manifold. Application of laparoscopic fundoplication to children is slowly but surely following this trend. This study evaluates our initial experience with pediatric laparoscopic Nissen fundopl...

CONTEXT Impairment of esophageal motility is a common finding in patients with gastroesophageal reflux disease (GERD) as reduced lower esophageal sphincter (LES) basal pressure. A very low LES pressure might facilitate the occurrence of more gastroesophageal reflux whereas abnormal esophageal peristalsis may contribute to impaired esophageal clearance after reflux. OBJECTIVE Evaluate the esop...

Background: Gastroesophageal reflux is a common problem in children, and (Gastroesophageal reflux disease) GERD comprises its objective pathologic sequelae, but the term has also been used more recently to denote symptoms affecting quality of life. The Clinical presentation is very variable. It causes mortality and morbidity without appropriate treatment plan. Objective: We are going to evaluat...

OBJECTIVES The aim of this study was to compare the different diagnostic approaches in detection of gastroesophageal reflux disease in children presented with symptoms suggesting gastroesophageal reflux disease. METHODS The study design was cross sectional. The study retrospectively included all children who underwent combined multiple intraluminal impedance and pH (pH-MII) monitoring due to ...

BACKGROUND/AIMS Functional constipation and gastroesophageal reflux disease are two major and commonly encountered components of childhood functional gastrointestinal disorders. Epidemiological studies in the adult population support that there is a significant overlap between the different functional disorders of the digestive tract. Therefore, we aimed to investigate the frequency of gastroes...

Pharmacological treatment of gastroesophageal reflux (GER) disease is mostly based on acid control. However, different molecules have been proposed both for patients with persisting symptoms and to limit adverse effects of proton pump inhibitors (PPI). This paper focuses on other acid inhibitors, alginate, prokinetics, drug acting on lower esophageal sphincter and esophageal hypersensitivity. M...

BACKGROUND Gastroesophageal reflux disease (GERD) is the most common cause of children admissions to pediatric gastroenterology unit and affects about 30% of pediatric population. Body weight and height percentiles of children with GERD and their relationship between presence and the severity of reflux on scintigraphic images were studied. METHODS Patients who underwent reflux scintigraphy be...