نتایج جستجو برای: monocyte chemoattractant protein 1

تعداد نتایج: 3630376  

Journal: :Hypertension 2007
Paulina Rivera María Paz Ocaranza Sergio Lavandero Jorge E Jalil

The RhoA/Rho kinase (ROCK) pathway is a new mechanism of remodeling and vasoconstriction. Few data are available regarding ROCK activation when angiotensin I-converting enzyme is high and blood pressure is normal. We hypothesized that ROCK is activated in the vascular wall in normotensive rats with genetically high angiotensin I-converting enzyme levels, and it causes increased vascular express...

Journal: :Journal of immunology 1998
P Proost S Struyf M Couvreur J P Lenaerts R Conings P Menten P Verhaert A Wuyts J Van Damme

Chemokines are important mediators in infection and inflammation. The monocyte chemotactic proteins (MCPs) form a subclass of structurally related C-C chemokines. MCPs select specific target cells due to binding to a distinct set of chemokine receptors. Recombinant and synthetic MCP-1 variants have been shown to function as chemokine antagonists. In this study, posttranslationally modified immu...

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