Despite the almost 50 yrs since the introduction of curative antituberculosis drugs, Mycobacterium tuberculosis continues to exert an enormous toll on world health, and tuberculosis remains the world's leading cause of death due to a single infectious agent. This has stimulated research efforts into finding new tools to tackle the continuing tuberculosis pandemic. One of the few successes to da...

The phylogenic analysis of the nucleotide sequences of the env gene has enabled classification of HIV-1 into three groups. The group M of HIV-1 infection has been classified into 9 different genetic subtypes A-K, with E and I being classified as circulating recombinants forms (CRFs). The groups O and N are less frequently encountered in human infections. Presently group M of HIV-1 globally caus...

From the Center for Pulmonary and Infectious Disease Control (CPIDC), Departments of Medicine and Microbiology and Immunology, University of Texas Health Center, Tyler (P.F.B.); and the Departments of Anatomy and Neurobiology, University of Arkansas for Medical Sciences and Medical Research Service, Central Arkansas Veterans Healthcare System, Little Rock (M.D.C.). Address reprint requests to D...

Malaria persists as an undiminished global problem, but the resources available to address it have increased. Many tools for understanding its biology and epidemiology are well developed, with a particular richness of comparative genome sequences. Targeted genetic manipulation is now effectively combined with in vitro culture assays on the most important human parasite, Plasmodium falciparum, a...

The emergence of "molecular epidemiology" as a scientific approach within the fields of epidemiology and toxicology has led to spirited discussion within the biomedical community, particularly in the area of cancer research. At scientific meetings and in peer-reviewed journals, numerous issues have been raised not only with regard to the practice of molecular epidemiology, but also with regard ...

Case Reports in Pulmonology publishes case reports and series all areas of pulmonology, prevention, diagnosis management pulmonary associated disorders, as well related molecular genetics, pathophysiology, epidemiology.