agility is the fundamental characteristic of a supply chain needed for survival in turbulent markets, where environmental forces create additional uncertainty resulting in higher risk in the supply chain management. in addition, agility helps providing the right product, at the right time to the consumer. the main goal of this research is therefore to promote supplier selection in pharmaceutica...

Much less has been reported on the stability of pyridoxinel than on the other vitamins that have been isolated in crystalline form. Such information is essential in studies of pyridoxine metabolism, in assays for the vitamin, and in the preparation and preservation of pharmaceutical products. In the present paper are presented data on the effect of light, heat, acids, alkali, and oxidizing agen...

This paper presents two new formulations of multiple-instance learning as a maximum margin problem. The proposed extensions of the Support Vector Machine (SVM) learning approach lead to mixed integer quadratic programs that can be solved heuristically. Our generalization of SVMs makes a state-of-the-art classification technique, including non-linear classification via kernels, available to an a...

A new sensitive, simple, rapid and precise reversed phase high performance liquid chromatographic (HPLC) and a spectrophotometric method has been developed for estimation of tolterodine in tablet dosage form. Chromatography was performed by using the mobile phase, Potassium Phosphate pH 4.5 and acetonitrile mixed by a low pressure gradient program. Hypersil BDS C18 column was used. The waveleng...

BACKGROUND Advertising affects consumer and prescriber behaviors. The relationship between pharmaceutical advertising and journals' publication of articles regarding dietary supplements (DS) is unknown. METHODS We reviewed one year of the issues of 11 major medical journals for advertising and content about DS. Advertising was categorized as pharmaceutical versus other. Articles about DS were...

In the present investigation, mixed-solvency approach has been applied for the enhancement of aqueous solubility of a poorly water- soluble drug, zaltoprofen (selected as a model drug), by making blends (keeping total concentrations 40% w/v, constant) of selected water-soluble substances from among the hydrotropes (urea, sodium benzoate, sodium citrate, nicotinamide); water-soluble solids (PEG-...

INTRODUCTION All medicines for human use are marketed with a package leaflet. Every package leaflet must contain an initial list mentioning all sections of the document in accordance to the European template Quality Review of Documents, being not to extensive, i.e. comprising approximately 1500 words. The so-called mixed leaflets contain information about medicines with more than one strength/ ...