A complex trait like crop yield is determined by its component traits. Multivariable conditional analysis in a general mixed linear model is helpful in dissecting the gene expression for the complex trait due to different effects, such as environment, genotype, and genotype× environment interaction. A recursive approach is presented for constructing a new randomvector that can be equivalently u...

Tracking by assignment is well suited for tracking a varying number of divisible cells, but suffers from false positive detections. We reformulate tracking by assignment as a chain graph–a mixed directedundirected probabilistic graphical model–and obtain a tracking simultaneously over all time steps from the maximum a-posteriori configuration. The model is evaluated on two challenging four-dime...

Analysis of collaborative e-test construction identified the number of testauthors as the most important factor in test validity, while test reliability depends more on participation of an expert. Based on these findings, a collaborative e-test construction system was developed that uses predicted response-time and score distributions to improve the reliability of tests constructed by novice te...

In this article, we present two formulations and their unification for the Mixed-Model Sequencing Problem with Workload Minimisation (MMSP-W) for production lines with serial workstations and parallel homogeneous processors. The models were executed in Solver CPLEX, with reference instances and with a case study of Nissan’s Powertrain plant in Barcelona. Different situations were analysed to ev...

In this contribution, linearized dynamic model of Cumulative Mass Fraction (CMF) of Potassium Nitrate-Water Seeded Continues Mixed Suspension Mixed Product Removal (CMSMPR) crystallizer is approximated by a simplified model in frequency domain. Frequency domain model simplification is performed heuristically using the frequency response of the derived linearized models data. However, the CM...

A new measure for reliability of a rating scale is introduced, based on the classical definition of reliability, as the ratio of the true score variance and the total variance. Clinical trial data can be employed to estimate the reliability of the scale in use, whenever repeated measurements are taken. The reliability is estimated from the covariance parameters obtained from a linear mixed mode...

The goal of this paper is to review the main results offered by some experimental paradigms to support morphological processing of visual isolated words. Three theoretical hypotheses proposing different solutions to the role of word morphological structure in lexical access and representation are described: a) full parsing, b) full listing and c) mixed models. Data from morphologically structur...

this paper studies the hybrid flow shop scheduling where the optimization criterion is the minimization of total tardiness. first, the problem is formulated as a mixed integer linear programming model. then, to solve large problem sizes, an artificial immune algorithm hybridized with a simple local search in form of simulated annealing is proposed. two experiments are carried out to evaluate th...

This paper improves and extends the two-step penalized iterative estimation procedure for the linear mixed effect model (LMM) by explicitly penalizing the off-diagonal components of the covariance matrix of random effects. To explicitly penalize the off-diagonal terms in the covariance matrix of random effects, glasso is incorporated in the penalized LMM approach. The paper also provides theore...

Inference in Generalized linear mixed models with multivariate random effects is often made cumbersome by the high-dimensional intractable integrals involved in the marginal likelihood. An inferentialmethodology based on themarginal pairwise likelihood approach is proposed. This method belonging to the broad class of composite likelihood involves marginal pairs probabilities of the responses wh...