this study was performed to design bilayer regioselective floating tablets of atenolol and lovastatin to give immediate release of lovastatin and sustained release of atenolol. bilayer floating tablets comprised two layers, i.e immediate release and controlled release layers. the immediate release layer comprised sodium starch glycollate as a super disintegrant and the sustained release layer c...

We study a problem faced by a major beverage producer. The company produces and distributes several brands to various customers from its regional distributors. For some of these brands, most customers do not have enough demand to justify full pallet shipments. Therefore, the company decided to design a number of mixed or “rainbow” pallets so that its customers can order these unpopular brands w...

In this paper, we review existing discontinuous Galerkin (DG) methods for elasticity and introduce a new formulation based on mixed finite elements. We highlight the subtle and important differences between Interior Penalty (IP) and mixed FEM based methods. In the mixed method for elasticity, choices of function spaces for approximating primal and dual variable is non-trivial for two main reaso...

this paper presents an application of benders decomposition to deal with the complexities in the simultaneous generation expansion planning (gep) and transmission expansion planning (tep). unlike the power system operation fields of study, the power system planning methods are not expected to be fast. however, it is always preferable to speed up computations to provide more analysis options for...

‎We study dual integral equations which appear in formulation of the‎ ‎potential distribution of an electrified plate with mixed boundary‎ ‎conditions‎. ‎These equations will be converted to a system of‎ ‎singular integral equations with Cauchy type kernels‎. ‎Using‎ ‎Chebyshev polynomials‎, ‎we propose a method to approximate the‎ ‎solution of Cauchy type singular integral equation which will ...

In this article, an adaptive least-squares mixed finite element method is studied for pseudo-parabolic integro-differential equations. The solutions of least-squares mixed weak formulation and mixed finite element are proved. A posteriori error estimator is constructed based on the least-squares functional and the posteriori errors are obtained. Keywords—Pseudo-parabolic integro-differential eq...

Recently Masud and Hughes proposed a stabilized mixed finite element formulation for Darcy flow. An interesting feature of this formulation is that there are no mesh-dependent parameters. In the present work we provide a derivation of this formulation based on a multiscale decomposition of the solution. We also extend the work of Masud and Hughes to three-dimensional problems and show the conve...