The stochastic simulation algorithm commonly known as Gillespie's algorithm (originally derived for modelling well-mixed systems of chemical reactions) is now used ubiquitously in the modelling of biological processes in which stochastic effects play an important role. In well-mixed scenarios at the sub-cellular level it is often reasonable to assume that times between successive reaction/inter...

in the present work, multidimensional modeling of open-cycle process of om355 engine was developed. calculations for computational mesh were carried out. the results of the model were validated by experimentally measured in-cylinder pressure and the good agreement between calculations and measurements approved the trustworthy of numerical code. results included pressure, temperature, emission a...

The present paper continues the study (begun by Quattrocchi, Colouring 4-cycle systems with specified block colour pattern: the case of embedding P3-designs, Electron. J. Combin., 8 (2001)) of 4-cycle systems with specified block colour patterns that are also strict colourings in the sense of Voloshin (Coloring Mixed Hypergraphs: Theory, Algorithms and Applications, American Mathematical Societ...

By integrating heterogeneous functional genomic datasets, we have developed a new framework for detecting combinatorial control of gene expression, which includes estimating transcription factor activities using a singular value decomposition method and reducing high-dimensional input gene space by considering genomic properties of gene clusters. The prediction of cooperative gene regulation is...

Exergy and thermoeconomic analyses are herein employed to evaluate the proposed refrigeration cycle of Tabriz olefin plant. The exergetic and exergoeconomic variables of all equipment and streams are calculated. Thermoeconomic model is developed according to the total revenue requirement (TRR) method. The results indicate that the rational efficiencies of the Heat Exchanger E-104 and compressor...

A mixed hypergraph is a tripleH = (X, C,D), whereX is the vertex set and each of C, D is a family of subsets of X, the C-edges and D-edges, respectively. A proper k-coloring of H is an injective mapping c : X → {1, . . . , k} such that each C-edge has two vertices with a common color and each D-edge has two vertices with distinct colors. Maximum number of colors in a coloring using all the colo...

We describe a method for the generation of random point deletions in any target DNA sequence using synthetic mixed oligonucleotides. A mixed pool of oligonucleotides, which contain single nucleotide deletions randomly distributed throughout the full length, was generated by a modification of the synthesis cycle of an automated DNA synthesiser that allowed the inefficient incorporation of nucleo...

We propose a new concept for the analysis of games, the TASP, which gives a precise prediction about non-equilibrium play in games whose Nash equilibria are mixed and are unstable under fictitious play-like learning processes. We show that, when players learn using weighted stochastic fictitious play and so place greater weight on more recent experience, the time average of play often converges...

Given a weighted directed hypergraph H = (V,EH ;w), where w : EH → R+, we consider the problem of embedding all weighted directed hyperedges on a mixed cycle, which consists of undirected and directed links. The objective is to minimize the maximum congestion of any undirected or directed link in the mixed cycle. In this paper, we first formulate this new problem as an integer linear program, a...

We studied patterns of oscillatory neural activity in the network that generates respiratory rhythm in mammals. When isolated in vitro, this network spontaneously generates an inspiratory-related motor rhythm, with stable amplitude from cycle to cycle. We show that progressively elevating neuronal excitability in vitro causes periodic modulation of this inspiratory rhythm, evoking (in order): m...