cognitive impairment may be a common even at the onset of multiple sclerosis (ms). in this case-control study, we tried to find out the probable relationship between homocysteine levels and cerebral atrophy or cognitive impairment in patients with multiple sclerosis. one hundred fifty six patients who had ms according to mcdonald diagnostic criteria were included in this study. patients’ age, g...

introduction: studies with single photon emission computed tomography (spect) have revealed inconsistent changes of regional cerebral blood flow (rcbf) in schizophrenia. some studies investigated the rcbf and its relationship with psychopathology, positive and negative symptoms in treated patients. however, there is a little information about the pattern of rcbf in recently untreated or never t...

to investigate the effects of the two-pore-domain potassium (k2p) channel task-3 in a syngeneic murine model for malignant glioma. malignant or high-grade glioma (who grade iii and iv) are the most common and most aggressive primary brain tumors in adults. despite aggressive multimodal therapy, the outcome of patients with malignant glioma remains poor. however, recent phase i and ii trials hav...

in 1890, coley observed that cancer patients who developed infections had smaller tumors. from this, he developed coley’s toxin and treated tumors with injections of infectious materials. in 1960s,  mahaley used monoclonal antibodies to treat central nervous system(cns)  tumors, that research and clinical investigations in brain tumor immunotherapy became a serious undertaking. there are severa...

background traumatic brain injury (tbi) is an important public health problem throughout the world. objectives the aim of this study was to assess repeated glasgow coma scale (gcs) scores in predicting the severity of tbi and patients’ survival. patients and methods in this longitudinal study used a total sample of 239 patients, all of whom were hospitalized with traumatic brain injuries. subje...

introduction: the basic objective of this study is to investigate the effects of alpha and theta brain waves amplitude increase in occipital area on reducing the severity of symptoms of generalized anxiety disorder and to increase the global functioning level in patients with gad. methods: this study is a quasi-experimental study with pre-test and post-test with two groups. for this purpose, 28...

anxiety and depression are the most frequently diagnosed psychological diseases showing a high co-morbidity. they have a severe impact on the lives of the persons concerned. the physical, mental and social benefits of exercise have been well-documented. in iran, mental disorders are one of the largest sources of disease burden. the aim of this paper is to critically review the currently availab...

conclusions results of this study indicate that selective brain cooling is an effective method of decreasing icp in rats; however, the deeper hypothermia caused a greater decrease in icp three hours after hypothermia induction. background experimental approaches have been promising with the use of therapeutic hypothermia after traumatic brain injury (tbi) whereas clinical data have not supporte...

background: early diagnosis of brain tumors has significant effect on the treatment process. brain metastatic tumors are usually diagnosed following the neurological symptoms in patients or incidentally after computerized tomography (ct) scan and magnetic resonance imaging (mri) requests of the brain. objectives: implementation of a new method for being informed about the origin of brain tumors...

objective head injury (hi) is the leading cause of mortality and life-long disability for infants. infants have different anatomical and pathophysiological brain structures from other age groups. this study surveys infant hi patients admitted to shahid beheshti hospital in kashan, iran from 2004–2010 to identify the causes of his in infants. materials and methods in this retrospective study, al...