The recurrent aphthous ulcer (RAU) is a pathological change found in the oral mucosa, characterized by painful single or multiple ulcers. The etiologic aspect of RAU is not well understood; however it is known that due to lower CD4 cell counts patients had higher prevalence of these oral lesions, and immunosuppressed patients with HIV are predisposed. Patient FC is African descent, 26 years old...

Attempts were made to demonstrate herpes simplex virus (HSV) type 1 and type 2, varicella zoster virus (VZV) and cytomegalovirus (CMV) in specimens obtained from aphthous ulceration lesions by the immunofluorescent method using fluorescein-labeled monoclonal antibodies. HSV-1 and VZV were detected in 2 and 4 out of 30 patients, respectively. Although almost all viruses that can infect the oral ...

Behçet's syndrome is a multi-systemic and chronic disorder that affects many organs. It has been suggested that the diagnosis was based on the presence of the 'major' and 'minor' clinical criteria. When thromobophlebitis, arthritis, central nervous system or gastrointestinal lesions are also present. Behçet's syndrome will be thought to be present in the appropriate geographic area. We report a...

INTRODUCTION The aetiology of recurrent aphthous stomatitis (RAS) remains unknown. An association between RAS and coeliac diseases (CD) has previously been suggested, but the supporting evidence remains equivocal. The aim of the present study was to determine the likely frequency of CD in a large cohort of patients with well-defined RAS, by detailed haematological and serological analysis, incl...

The release of 51Cr from labelled colon cells was used to assess a possible lymphocytotoxic effect of peripheral blood lymphocytes from patients suffering from recurrent aphthous ulceration. No significant (p > 0.03) difference was observed between the isotope release following incubation with patients' or control lymphocytes. The absence of such a lymphocytotoxic effect, detectable with oral e...

Nowadays, etiopathogenesis of recurrent aphthous stomatitis is not fully understood. Chronic gastritis, gastric and duodenal ulcers, diseases associated with H. Pylori, often attend this oral pathology. It is acknowledged, that H. Pylori is a conditional-pathogenic microbe which is included in normal mucosalflora of the gastrointestinal tract and oral cavity. Oral cavity appears to be a seconda...

Background: The current treatments of recurrent aphthous stomatitis are not very effective and are not justified for long term using due to their potential side effects. Objective: To compare the efficacy of topical sucralfate mouthwash with topical tetracycline mouthwash in recurrent aphthous stomatitis. Patients and Methods: In a randomized matched clinical trial, 60 patients with recur...