Extension of ultra-high-throughput experiment (UHTE) approaches to new assay methodologies is often limited by compromised data quality when samples are miniaturized. Overcoming this challenge requires attending to all components of an automated laboratory system contributing to assay variability. A key but often neglected source is the high-density multiwell platform or microtiter plate. Mater...

During this decade, the design of small-size wireless communication devices was key topic in the field of communication engineering. The design of miniaturized antenna is an important parameter to reduce the overall size of the wireless communication devices. Many approaches have been proposed to design the miniaturized antennas. Recently, fractal antenna geometry has been employed to design th...

In a previous study, we concluded that a conductivity based PCO2 sensor is an attractive solution for early detection of ischemia and presented two design geometries. For organ surface measurements, the planar design was suitable but it was difficult to insert the sensor into the tissue. A cylindrical design solution was favored for insertion due to the large membrane contact area and easy plac...

in recent years, biosurfactants due to wide applications in chemical, petroleum, food andpharmaceutical industries, have been widely considered by researchers. biosurfactants are produced by aseries of microorganisms, so it is important to screen culture medium and operating conditions in miniaturized bioreactors prior to scaling up to large bioreactors.in this study, using a kind of miniaturiz...

Fluidized beds are suspensions of grains by ascending fluids in tubes, and commonly used industry given their high rates mass heat transfers between the solids fluid. Although usually employed large scales (tube diameter order meter), fluidized have a great potential much smaller (order millimeter) for processes involving powder fluids. Of particular interest is pharmaceutical industry, which c...

Background: Multidrug-resistant tuberculosis (MDR-TB) is posing a major threat to global TB control. In this study, we focused on two consecutive MDR-TB isolated from the same patient before and after the initiation of anti-TB treatment. To better understand the genomic characteristics of MDR-TB, Single Molecule Real-Time (SMRT) Sequencing and comparative genomic analyses was performed to ident...

A method for conducting fast and efficient gas chromatography based on short multicapillaries in straight alignment combined with atomic emission detection was developed for field analysis. The strategy enables for speciation analysis of organometallic compounds. The analytes are simultaneously ethylated and preconcentrated on a solid phase microextraction (SPME) fiber placed in the headspace o...

BACKGROUND Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sialic acid following incubation of NA with substrate in the presence of serum. I...