A long-term study, using male Wistar rats, was initiated to determine whether the effects of dietary constituents on AFB1-induced liver cancer could be associated with altered microsomal enzyme activity. They were maintained on mice pellets mixed with specific dietary constituents for 7 days and then given a single carcinogenic dose of AFB1 (500 micrograms/rat). After three months, the dietary ...

Male Donryu, Wistar King rats showed discontinuous variations in hepatic microsomal UDP-glucuronyltransferase activities towards androsterone, but not towards testosterone, bilirubin, phenolphthalein and 4-nitrophenol. Fresh microsomal fraction with a low transferase activity towards androsterone formed 0.049--0.080 nmole of glucuronide/min per mg of protein, whereas fresh microsomal fraction w...

A microsomal preparation from chick embryo cartilage has been shown to catalyze the incorporation of sulfate-36S from 3’-phosphoadenosine 5’-phosphosulfate-3% into microsomal glycosaminoglycan. This enzyme preparation is the same preparation that previously has been shown to catalyze the formation of chondroitin (nonsulfated) from sugar nucleotide precursors. The microsomal sulfate acceptor app...

This paper introduces the circulating processor model for parallel computer systems The circulating processor model is a product form queueing network model where the processors are allowed to circulate between the parallel applications instead of the more traditional circulating task model Certain behaviors of parallel systems are better captured using this new approach The circulating process...

s presented at the AAO-HNS Annual Meeting. Otolaryngol Head Neck Surg 2006;135:197–203. 3. Karri V. Randomised clinical trials in plastic surgery: survey of output and quality of reporting. J Plast Reconstr Aesthet Surg 2006;59:787–96. 4. Bhattacharyya N. Peer review: studying the major otolaryngology journals. Laryngoscope 1999;109:640–4. 5. Noordzij J, Affleck B. Coblation versus unipolar ele...

Specific degradation of the phospholipid membrane of guinea-pig liver microsomal fraction with phospholipase A inactivated glucuronyltransferase. The inactivation was reversed by phosphatidylcholine and mixed microsomal phospholipid micelles at concentrations similar to those present in intact microsomal preparations. The other commonly occurring phospholipids did not reactivate phospholipase A...

Postnatal developmental changes in hapatic microsomal UDP-glucuronyltransferase were studied in the rat. The previously reported postnatal decline in the capacity of microsomal fractions to glucuronidate p-nitrophenol was found to be observable in unperturbed preparations only at non-saturating concentrations of the substrate UDP-glucuronic acid. At saturating concentrations of UDP-glucuronic a...

Testicular microsomal fraction (10,000•`105,000 •~ g precipitates) of adult rats which was responsible for enzymic transformation of pregnenolone into testosterone was inactivated by phospholipases C and D, but not by phospholipase A . After the 10 kilocycles/sec. sonication for 60 mins., most of the microsomal enzyme activities were still found in the 105,000 •~ g precipitates. The specific ac...