Sensitive immunocytochemical and molecular assays allow the detection of single circulating tumor cells (CTC) in the peripheral blood and disseminated tumor cells (DTC) in the bone marrow as a common and easily accessible homing organ for cells released by epithelial tumors of various origins. The results obtained thus far have provided direct evidence that tumor cell dissemination starts alrea...

Intraglomerular metastasis is a rare manifestation of disseminated malignancies. We present here a case of intraglomerular metastatic carcinoma diagnosed as an incidental finding on a kidney biopsy in a 62-year-old male presenting with acute renal failure and metastatic penile squamous cell carcinoma. A proliferative lesion composed of highly atypical epithelial cells was found within a capilla...

Cancer Control 601 The emergence of sentinel lymph node (SLN) biopsy as an alternative method to axillary dissection for staging the axilla in breast cancer patients has brought the value of axillary dissection into close scrutiny. In addition, it has stimulated the assessment of the biologic implications of micrometastatic disease to lymph nodes. Historical review of SLN technology demonstrate...

Abstract Case Summary Melanoma of the abdominal wall is not uncommon, and sentinel lymph nodes are usually located in lymphatic drainage basins axilla or inguinal region. Less frequently, interval can be found along vessels between primary cancer nearest basin. We present case a 53-year-old female with silicone breast implants who underwent scar excision node biopsy for 1mm Breslow thickness su...