Retinopathy is one of the clinical signs of hemoglobin SC disease.1 It is often misunderstood and diagnosed late because it is initially asymptomatic due to its preferential localization in the periphery of the retina.2,3 A 25-year-old man from the Ivory Coast was admitted because of an abdominal pain crisis. The patient, who had sickle cell trait, had mild scleral jaundice and pronounced splen...