نتایج جستجو برای: micro vessel density

تعداد نتایج: 597580  

2017
Harsha L Rao Zia S Pradhan Robert N Weinreb Mohammed Riyazuddin Srilakshmi Dasari Jayasree P Venugopal Narendra K Puttaiah Dhanaraj A S Rao Sathi Devi Kaweh Mansouri Carroll A B Webers

PURPOSE To compare the diagnostic abilities of vessel density measurements of the optic nerve head (ONH), peripapillary and macular regions on optical coherence tomography (OCT) angiography in eyes with primary open angle glaucoma (POAG) with that of the ONH rim area, peripapillary retinal nerve fiber layer (RNFL) thickness and the macular ganglion cell complex (GCC) thickness measurements. M...

2012
Daniela Mihic-Probst Kristian Ikenberg Marianne Tinguely Peter Schraml Silvia Behnke Burkhardt Seifert Gianluca Civenni Lukas Sommer Holger Moch Reinhard Dummer

Recent molecular studies provide evidence for a significant transcriptional plasticity of tumor cell subpopulations that facilitate an active contribution to tumor vasculature. This feature is accompanied by morphological changes both in vitro and in vivo. Herein, we investigated the morphological plasticity of tumor cells with special focus on vasculogenic mimicry and neovascularisation in hum...

2017
Volker J. Schmidt Jennifer M. Covi Christoph Koepple Johannes G. Hilgert Elias Polykandriotis Amir K. Bigdeli Luitpold V. Distel Raymund E. Horch Ulrich Kneser

BACKGROUND The arteriovenous (AV) loop model enables axial vascularization to gain a functional microcirculatory system in tissue engineering constructs in vivo. These constructs might replace surgical flaps for the treatment of complex wounds in the future. Today, free flaps are often exposed to high-dose radiation after defect coverage, according to guideline-oriented treatment plans. Vascula...

2015
A Carsetti S Pierantozzi HD Aya S Bazurro A Donati A Rhodes M Cecconi

Objectives The aim of this study was to assess the accuracy of microvascular density parameters (total vessel density (TVD), perfused vessel density (PVD) and proportion of perfused vessels (PPV)) obtained by the new automatic analysis software CytoCamTools 1.7.12 (CC) (Braedius, Amsterdam, The Netherlands) in comparison with Automated Vascular Analysis (AVA) software 3.2 (MicroVision Medical, ...

2011
Moses M. Darpolor Robert C. Molthen Kathleen M. Schmainda

BACKGROUND This study demonstrates that a dynamic susceptibility contrast-magnetic resonance imaging (DSC-MRI) perfusion parameter may indicate vascular abnormality in a brain tumor model and reflects an effect of dexamethasone treatment. In addition, X-ray computed tomography (CT) measurements of vascular tortuosity and tissue markers of vascular morphology were performed to investigate the un...

Journal: :Head & neck 2015
Sandro Pasquali Maria Cristina Montesco Chiara Ginanneschi Gianna Baroni Clelia Miracco Carmelo Urso Fabio Mele Anna Rita Lombardi Pietro Quaglino Laura Cattaneo Stefania Staibano Gerardo Botti Paolo Visca Marina Zannoni Giuseppe Soda Barbara Corti Luca Pilloni Luca Anselmi Amelia Lissia Margherita Vannucchi Cristina Manieli Daniela Massi

BACKGROUND Scalp/neck melanomas have a poor prognosis, possibly because of a rich vascular supply that prompts tumor cells' dissemination. METHODS We compared the accuracy of immunohistochemical (IHC) staining with morphology for the identification of lymphovascular invasion in 156 scalp/neck melanomas. We then analyzed the association of vessel invasion and density with pathological features...

Journal: :Investigative ophthalmology & visual science 2017
Jian Yu Kuanlin Xiao Jingjing Huang Xinghuai Sun Chunhui Jiang

Purpose To examine the retinal vasculature in patients with obstructive sleep apnea-hypopnea syndrome (OSAS) and to determine the correlation between retinal vascularity and the severity of OSAS. Design Prospective, cross-sectional study. Methods Sixty-nine consecutive subjects who underwent polysomnography were enrolled. Patients were divided into three groups according to the severity of ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2000
E L Lund C Thorsen M W Pedersen N Junker P E Kristjansen

In 21 human small cell lung cancer (SCLC) cell lines, we determined the expression of mRNA and secreted protein levels of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). The VEGF expression was highly variable between cell lines, with a > 100-fold variation, under identical in vitro conditions. The bFGF expression in cell lines was generally very low. Nine o...

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