The management of candidiasis, once effective, is becoming more and difficult with the increase resistance various Candida species to classical antifungals. It in this context that we reported our previous works pharmacochemical development new diazaheteroaryls derivatives functionalized a Michael acceptor such as arylpropenone, arylacrylonitrile arylcyanopropenone. These benzimidazolyl-arylpro...

an efficient synthesis of some novel coumarin derivatives via 1, 4- michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (csa) under solvent free conditions is described. the corresponding michael addition products were obtained in good to excellent yield. the synthesized compounds were screened for their antibacterial activity against e. coli, s. aureus and an...

the anticoagulant racemic warfarin is synthesized by the michael addition of 4-hydroxycoumarin with benzalacetone in the present of equimolar amounts of imidazolium based ionic liquids [bmim] bf4 and [bmim] br and other reaction solvents such as h2o, pyridine and ammonia in five different tests. also synthesis of a derivative of warfarin (2-methyl-4-phenyl pyrano [3, 2-c] chromen-5(4h)-one) und...

The rates of the epoxidation reactions of aldehydes, of the aziridination reactions of aldimines, and of the cyclopropanation reactions of α,β-unsaturated ketones with aryl-stabilized dimethylsulfonium ylides have been determined photometrically in dimethyl sulfoxide (DMSO). All of these sulfur ylide-mediated cyclization reactions as well as the addition reactions of stabilized carbanions to N-...

chraewcz, chrawcz, chrawecz, chreitz, chreucz, chreuecz, chreutz, chrevcz, chrevtz, chrewcz, chrewczt, chrewecz, chrewtz, chrvtz, creucz, crecz, creuecz, creutz, cretz, crewcz, crewtz, crucz, cruecz, cruetz, cruicz, cruitz, cruiz, crutz, crtz, cruytz, crvitz, crvtz, kraitz, kreevcz, kreitz, kreucz, krecz, kreuecz, kreutz, kretz, krevcz, krevecz, krewcz, krewtcz, krewtz, krewz, krucz, kruecz, kr...