A highly selective catalytic, one-step synthesis converts oleic acid into 9( I O)-carboxystearic acid in high yields (85-99%). Hydrocarboxylation with water and carbon monoxide under pressure (3000-4000 psi) is catalyzed with a mixture of palladium chloride and triphenylphosphine at 120-150 C with or without acetone or acetic acid solvents. Palladium supported on carbon is also an effective hyd...

A non-invasive method to characterize human mesenchymal stromal cells during adipogenic differentiation was developed for the first time. Seven fatty acid methyl esters (FAMEs), including methyl laurate, methyl myristate, methyl palmitate, methyl linoleate, methyl oleate, methyl elaidate and methyl stearate, were used for characterizing adipogenic differentiation using headspace solid-phase mic...

BACKGROUND Dietary fatty acids that are more prone to oxidation than to storage may be less likely to lead to obesity. OBJECTIVE The aim of this study was to determine the effect of chain length, degree of unsaturation, and stereoisomeric effects of unsaturation on the oxidation of individual fatty acids in normal-weight men. DESIGN Fatty acid oxidation was examined in men consuming a weigh...

BACKGROUND Catalytic deoxygenation is a prominent process for production of renewable fuels from vegetable oil. In this work, deoxygenation of technical grade methyl oleate to diesel fuel aliphatic hydrocarbons (C15 - C18) is evaluated with several parameters including temperature, hydrogen pressure and reaction time in a stirred batch reactor over Pd/SBA-15 catalysts. RESULTS Two different S...

The effects of long-chain (LC) fatty acids on rate of heat production (heat rate) and mitochondrial membrane potential (DeltaPsi) of intact guinea pig cardiac muscle were investigated at 37 degrees C. Heat rate of ventricular trabeculae was measured with microcalorimetry, and DeltaPsi was monitored in isolated ventricular myocytes with either JC-1 or tetramethylrhodamine ethyl ester (TMRE). Met...

To elucidate the mechanism of impaired serum binding of furosemide observed in patients with renal dysfunction, we examined in vitro the serum protein binding of furosemide in the absence and presence of uremic toxins that are endogenously retained solutes in uremic serum and act as inhibitors of drug binding. Analysis of the binding data of furosemide at its therapeutic concentration (6.6 mg/L...

In the present study, catalytic activity of dense, porous, electrospun membranes polysulfone (PSF) and with sulfonated polystyrene (PSF_PSS) have been evaluated in reactions esterification oleic acid methanol, times that varied from 10 to 480 minutes. Conversion biodiesel has confirmed by FTIR quantified through gas chromatography. The results showed catalysts used were effective reaction studi...