The subcutaneous and systemic injection of serotonin reduces cutaneous and visceral pain thresholds and increases responses to noxious stimuli. Different subtypes of 5-hydroxytryptamine (5-HT) receptors are suggested to be associated with different types of pain responses. Here we show that serotonin also inhibits catechol O-methyltransferase (COMT), an enzyme that contributes to modultion the ...

Amritotharanam Kashyam, a specific Ayurvedic drug, was the focus of current inquiry to evaluate its efficacy. For liver and digestive-related issues, this medication is suggested. This obtained from standard vendor in Chennai (India), GC-MS analysis carried out according procedure. A few critical biomolecules include benzoic acid, hexadecanoic 6,9-octadecadienoic 9-octadecenoic methyl ester (E)...

2,4,5-Trihydroxytoluene (THT) oxygenase from Burkholderia sp. strain DNT catalyzes the conversion of THT to an unstable ring fission product. Biochemical and genetic studies of THT oxygenase were undertaken to elucidate the mechanism of the ring fission reaction. The THT oxygenase gene (dntD) was previously localized to the 1.2-kb DNA insert subcloned in the recombinant plasmid designated pJS76...

The electrochemical oxidation of dopamine, 4-methylcatechol, dihydroxyphenylacetic acid, dihydroxyphenyl ethylene glycol, and hydroquinone was examined on several native and modified glassy carbon (GC) surfaces. Treatment of polished GC with pyridine yielded small ∆Ep values for cyclic voltammetry of all systems studied, implying fast electron-transfer kinetics. Changes in surface oxide coverag...

The fabrication of an optical biosensor by using stacked films where 3-methyl-2-benzothiazolinone hydrazone (MBTH) was immobilized in a hybrid nafion/sol-gelsilicate film and laccase in a chitosan film for the detection of phenolic compounds wasdescribed. Quinone and/or phenoxy radical product from the enzymatic oxidation ofphenolic compounds was allowed to couple with MBTH to form a colored az...

Copigmentation has been suggested as a main colour stabilising mechanism in plants protecting the coloured flavylium cation from the nucleophilic attack by the water molecule. In this study influence of phenolic compounds addition (catechol, 4-methyl catechol, (+)-catechin and gallic acid) on stability of red currant juice anthocyanins (copigment:pigment molar ratio 50:1 and 100:1) during 30 da...

background pyrocatechol or 1, 2-dihydroxybenzene, or 2-hydroxyphenol is considered as apriority pollutant since it is harmful to organisms at low concentrations, and has been classified as hazardous pollutants. objectives the objective of this study was to examine whether azolla filiculoides, is able to remove pyrocatechol from aqueous solutions. materials and methods this study is an experimen...