In this paper we report a search for intermediate mass magnetic monopoles and nuclearites using CR39 and Makrofol Nuclear Track Detectors (NTDs) of the SLIM large area experiment, 440 m exposed at the high altitude laboratory of Chacaltaya (Bolivia) and about 100 m at Koksil, Himalaya (Pakistan). We discuss the new chemical etching and improved analysis of the SLIM CR39 sheets. Preliminary limi...

2014 The photoionization absorption spectrum of the strongly Cr-doped GaAs samples was measured in the energy region 5 500-11 000 cm-1 under hydrostatic pressure up to 9 kbar at 300 K and 77 K. The EPR measurements with 1.09 03BCm laser excitation shows that this absorption is due to the charge transfer Cr3+ ~ Cr2+ transitions. The theoretical model which takes into account the lattice relaxati...

This study was performed to design bilayer regioselective floating tablets of atenolol and lovastatin to give immediate release of lovastatin and sustained release of atenolol. Bilayer floating tablets comprised two layers, i.e immediate release and controlled release layers. The immediate release layer comprised sodium starch glycollate as a super disintegrant and the sustained release layer c...

This study was performed to design bilayer regioselective floating tablets of atenolol and lovastatin to give immediate release of lovastatin and sustained release of atenolol. Bilayer floating tablets comprised two layers, i.e immediate release and controlled release layers. The immediate release layer comprised sodium starch glycollate as a super disintegrant and the sustained release layer c...

This learning's objective is to determine and investigate how pharmaceutical restrictions affect the characteristics of gastric floating tablets using diclofenac sodium (DICL) as a model for solubility enhancement, sodium-bicarbonate (NaHCO3) or calcium-carbonate (CaCO3). Hydroxypropyl Methylcellulose (HPMC) swelling polymer K100M K15M gas-forming substance. BY direct-compression manufacturing ...

the purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. a 32 full factorial design was employed to study the effect of independent variables like carbopol-934p and hydroxypropyl methylcellulose k100m, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...

Abstract Orodispersible films comprise a promising dosage form with wide range of advantages compared to conventional formulations. The electrospinning process can significantly enhance the relevant characteristics orodispersible films, e.g., dissolution rate and ease administration. This study involved use two types hydroxypropyl methylcelluloses low molecular weight obtained from three differ...

To prolong the residence time of dosage forms within the gastrointestinal tract until all drug is released at the desired rate is one of the real challenges for oral controlled-release drug delivery systems. This study was designed to develop a controlled-release floating matrix tablet and floating raft system of Mebeverine HCl (MbH) and evaluate different excipients for their floating behavior...

Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain and discomfort which are having shorter half life (1.1hour) with the dose administration of 3-4 times a day. The aim of the study was to prepare and evaluate the Chlorzoxazone sustained release tablets in order to reduce the dose frequency and to improve the patient compliance. The tablets were...

objective: hexavalent chromium [cr (vi)] compounds are well-known environmental contaminants  generated from industrial processes. several studies have reported the harmful effects of cr (vi) on different organs, however, little is known about neurotoxic effects of cr (vi). the aim of this study is to investigate the toxic effects of cr (vi) on pc12 cells. methods: pc12 cells were cultured foll...