Orthosiphon stamineus Benth (Family: Lamiaceae) or locally known as Misai Kucing has been widely used in Malaysia for treating kidney problems, gout, and diabetes. This study aims to evaluate the possible toxic effect after following fourteen days oral administration of methanol extract of O. stamineus in female Sprague Dawley (SD) rats. Control groups were treated orally with distilled water (...

Toxoplasma gondii is a zoonotic protozoa of economic significance in livestock. Infected livestock meat and products act as a source of T. gondii infection in humans. Current drugs against T. gondii are limited by hypersensitivity and toxicity, and are not effective against the encysted bradyzoite stage of T. gondii. Thus, there is urgent need for safe and effective therapeutic agents against T...

Free radical-mediated oxidation is often linked to various degenerative diseases. Biological substrates with lipids as major components are susceptible to oxygen-derived lipid peroxidation due to their composition. Lipid peroxide products act as biomarkers in evaluating the antioxidant potential of various plants and functional foods. The study focused on evaluation of the antioxidant potential...

The present study was designed to investigate the antioxidant activity of aqueous and methanol extracts of Erythrina indica Lam leaves by in vitro methods viz. 1, 1-Diphenyl-2-Picrylhydrazyl, nitric oxide radical scavenging activity, and inhibition of lipid peroxidation by thiobarbituric acid reactive substances (TBARS) method on isolated rat liver tissues. Quantitative analysis of antioxidativ...

the present work examines the protective mechanisms of methanol extract of oldenlandia umbellata (meou) in carbon tetrachloride intoxicated rats. rats were treated with carbon tetrachloride at the dose of 1 ml/kg body weight intraperitonially once in every 72 hrs for 16 days. the hepatoprotective activity of methanol extract of oldenlandia umbellata was evaluated by measuring levels of serum ma...

Phytochemicals are widely used as biocontrol agent against vector mosquitoes. The present study was undertaken to isolate and evaluate the mosquitocidal activity of various extracts of berries of S. nigrum against Culex quinquefasciatus. Crude and chloroform: methanol (1:1, v/v) extracts of fresh, mature, green berries of S. nigrum were tested against Cx. quinquefasciatus. The lethal concentrat...

The plant Krameria pauciflora MOC et. Sessé ex DC. is used as an anti-inflammatory and antidiabetic in traditional medicine. The aim of this study was to evaluate the in vivo anti-inflammatory and antidiabetic effects of a methanol extract from the roots of K. pauciflora. Dichloromethane and ethyl acetate extracts obtained by partitioning the methanol extract were also evaluated. Complete metha...

OBJECTIVE To investigate the larvicidal and ovicidal efficacy of different extracts of Cardiospermum halicacabum L. against Culex quinquefasciatus Say and Aedes aegypti L. (Diptera: Culicidae). MATERIALS AND METHODS Larvicidal efficacy of the crude leaf extracts of Cardiospermum halicacabum with five different solvents like benzene, hexane, ethyl acetate, methanol and chloroform was tested ag...

The objectives of this study was to evaluate the possible in vitro antioxidant potential and analysis of the active polyphenols in ethyl acetate and methanol extracts of leaves of Leonurus sibiricus L. Alcoholic extraction of Leonurus sibiricus leaf was carried out in two different solvents (ethyl acetate and methanol) on the basis of their different polarity. The in vitro antioxidant efficacy ...

OBJECTIVE Dracocephalum kotschyi (Lamiaceae family) has been used in traditional medicine for stomach and liver disorders, headache and congestion. In the present study, we have investigated phytochemical properties and antioxidant activities of dichloromethane, ethyl acetate and methanol extracts of D.kotschyi. MATERIAL AND METHODS Antioxidant activities of extracts were evaluated using the ...