carcinoid tumor is a slow-growing type of neuroendocrine tumor, originating in the enterochromaffin cells and secreting mainly serotonin. the diagnosis is based on clinical symptoms, hormone levels, radiological and nuclear imaging, and histological confirmation. the clinical symptoms are characterized by flushing, diarrhea, abdominal pain, telangiectasia and/or bronchoconstriction. however, mo...

The successful treatment of the rare malignancy eccrine porocarcinoma (EP) is extremely challenging, often not rewarding and when associated with metastatic disease, therapy results are disappointing. We present a unique case of treatment response of metastatic EP, with a significant disease-free interval. The patient has remained in clinical and radiological remission for 36 months since diagn...

STUDY OBJECTIVES To determine whether there is an association between cigarette smoking and the development of pulmonary metastatic disease among women with breast cancer. DESIGN A case-control study. SETTING The University of California, Davis Medical Center. PARTICIPANTS Eighty-seven women patients with unilateral, invasive breast cancer and pulmonary metastatic disease were identified ...

Male breast cancer is one of the rare malignancies. Clinically it usually a fixed mass in the breast in the seventh decade of life. Metabolic disorders and gyneco­mastia and Klinefelter's syndrome are important predis­r,osing factors.  Primary management is simple mastectomy plus re­gio:ial lymph node irradiation. In late cases or metastatic disease, orchidectomy, adrenalectomy, and hypophysec...

BACKGROUND The coracoid process of the scapula is a rare site of involvement for metastatic disease or for primary tumors. We are unaware of any reports in the literature of pathologic coracoid process fractures and only one report of metastatic disease to the coracoid. METHODS AND RESULTS In this case report, we present two cases with metastatic breast carcinoma of the coracoid process, one ...

OBJECTIVE We describe the case of a patient with metastatic breast cancer who presented with eyelid margin thickening and madarosis more suggestive of sebaceous cell carcinoma than metastatic disease. Histopathology confirmed metastatic breast adenocarcinoma. CASE REPORT A 59-year-old woman with a known history of metastatic breast carcinoma actively enrolled in a clinical trial presented wit...

The cranial nerves are often involved in head and neck malignancies. Some malignancies have a strong propensity to show perineural spread. Cranial nerve palsy may be the presenting sign of metastatic disease to the skull base. Like metastatic disease to the lungs or liver, the cranial nerves themselves may be the site of metastatic disease. In addition, cranial nerves can be injured by radiatio...

Metastatic tumors of the oral cavity are rare in occurrence. Renal cell carcinoma (RCC) metastasizes to organs head and neck 12–16% cases. RCC metastases tongue uncommon. A total 63 cases kidney cancer metastasizing have been reported literature. We report a clinical case metastasis skin lower eyelid (as initial manifestation disease) (11 months after diagnosis) one patient with metastatic canc...

Metastatic Crohn's disease, in which non-caseating granulomatous infiltration of the skin occurs at sites separated from the gastro-intestinal tract by normal tissue, is the least common dermatologic manifestation of Crohn's disease. We report a 15-year-old girl with metastatic Crohn's disease presenting as granulomatous vulvar papules and nodules with typical histopathologic features. To the b...

Mucinous tumors of the pancreas are rare and the diagnosis of invasive carcinoma can be a dilemma. While metastatic disease from mucinous cystadenocarcinoma (MCAC) and invasive intraductal papillary mucinous neoplasms (IPMN) have been reported, no extraperitoneal mucinous cystic metastatic disease has been described. When metastatic, the overall survival rates for invasive adenocarcinoma, mucin...