Metastatic tumors of the oral cavity are rare in occurrence. Renal cell carcinoma (RCC) metastasizes to organs head and neck 12–16% cases. RCC metastases tongue uncommon. A total 63 cases kidney cancer metastasizing have been reported literature. We report a clinical case metastasis skin lower eyelid (as initial manifestation disease) (11 months after diagnosis) one patient with metastatic canc...

BCC: basal cell carcinoma HH: hedgehog IHC: immunohistochemistry mBCC: metastatic basal cell carcinoma SUFU: suppressor of fused INTRODUCTION Basal cell carcinoma (BCC) represents nearly 80% of nonmelanoma primary skin malignancies in the United States. However, metastatic BCC (mBCC) is exceedingly rare, difficult to treat, and associated with high mortality, yet it’s easily preventable. We rep...

BACKGROUND Crystal storing histiocytosis (CSH) is a rare disorder characterized by accumulation of histiocytes containing crystalline material inclusions. This entity can be misdiagnosed as infection or tumor. We present a case of idiopathic CSH mimicking metastatic squamous cell carcinoma in a cervical lymph node and review of literature regarding this rare entity. METHODS AND RESULTS The pa...

Thymic carcinoma is a rare epithelial malignancy differentiated from thymoma by the presence of cytologically malignant cells. There are few reports of the treatment of locally advanced or metastatic thymic carcinoma. We describe a patient who sought treatment for thymic carcinoma metastatic to pleura, pericardium, retroperitoneum, and neck nodes. He was treated with neoadjuvant etoposide, ifos...

Background To establish a set of consensus statements for the management metastatic renal cell carcinoma, total 12 urologists and clinical oncologists from two professional associations in Hong Kong formed an expert panel. Methods Through series meetings using modified Delphi method, panelists presented recent evidence, discussed experiences, drafted on several areas focus regarding carcinoma. ...

Abstract Background Lymph node metastasis is a major prognostic sign of colorectal carcinoma and an important indicator for individualized treatment. M2 macrophages play key role in carcinogenesis tumor development by enhancing invasiveness promoting lymph metastasis. The purpose this study was to investigate the effect CD163-positive on carcinoma. Methods Postoperative tissues were obtained fr...

colorectal cancer most commonly metastasizes to the liver and lung. metastatic colon carcinoma (mcc) to the breast is extremely rare. krukenberg tumor is an uncommon metastatic tumor of the ovary. case presentation: a 38 years woman presented with abdominal pain. in evaluation colon cancer was diagnosed at stage 3. folfox chemotherapy was done. after one year she developed krukenberg tumor. few...

the association of squamous cell carcinoma of the larynx with thyroid papillary carcinoma is an unusual finding. from 2004 to 2011, approximately 250 patients underwent laryngectomies due to squamous cell carcinoma of the larynx at the otolaryngology department of khalili hospital, affiliated with shiraz university of medical sciences, shiraz, iran. in three patients, synchronous occurrence of ...

Background: Metastatic upper tract urothelial carcinoma (mUTUC) is a malignant cancer associated with poor prognosis. Few studies have investigated the clinical outcome of recently developed combination regimen programmed cell death 1 (PD-1) inhibitor plus nab-paclitaxel in mUTUC.

The entity known as pituitary carcinoma has been traditionally defined a tumor of adenohypophysial cells that metastasizes systemically or craniospinally independent the histological appearance lesion. Reported cases have clinically and histologically resembled their non-metastatic counterparts were classified adenomas; majority initially diagnosed adenomas, with progression spread, diagnosis w...