نتایج جستجو برای: metapneumovirus

تعداد نتایج: 1382  

Journal: :The Journal of general virology 2007
Sander Herfst Miranda de Graaf Eefje J A Schrauwen Nancy D Ulbrandt Arnita S Barnes Kannaki Senthil Albert D M E Osterhaus Ron A M Fouchier Bernadette G van den Hoogen

Human metapneumovirus (hMPV), a newly discovered paramyxovirus, is associated with acute respiratory-tract illness, primarily in young children, individuals with underlying disease and the elderly. Two genetic lineages of hMPV circulate around the world, and viruses from these two lineages demonstrate antigenic differences. The clinical impact of hMPV warrants the development of vaccines. Recom...

2010
Joshua W. Hustedt Marietta Vazquez

Lower respiratory tract infections are one of the leading causes of morbidity and mortality in children worldwide. Recent technological advances in the field of molecular biology have allowed virologists to detect many previously undetected viral pathogens. Two of these, human metapneumovirus (hMPV) and human bocavirus (HBoV), are of particular clinical interest to pediatric health care provide...

2018
Jarrod J Mousa Elad Binshtein Stacey Human Rachel H Fong Gabriela Alvarado Benjamin J Doranz Martin L Moore Melanie D Ohi James E Crowe

Respiratory syncytial virus (RSV) is a major human pathogen that infects the majority of children by two years of age. The RSV fusion (F) protein is a primary target of human antibodies, and it has several antigenic regions capable of inducing neutralizing antibodies. Antigenic site IV is preserved in both the pre-fusion and post-fusion conformations of RSV F. Antibodies to antigenic site IV ha...

Journal: :Pediatrics 2014
Danielle L Webster Aaron H Gardner Thomas J Dye Ranjit S Chima

Human metapneumovirus (hMPV) is a relatively recent addition to the multiplicity of viruses causing respiratory illness in infants and children. Although well described in its ability to cause respiratory illness, there is limited data detailing the association of hMPV with neurologic complications. In this report, we describe 2 toddlers with hMPV infection who presented in status epilepticus a...

Journal: :The Journal of infectious diseases 2002
Teresa C T Peret Guy Boivin Yan Li Michel Couillard Charles Humphrey Albert D M E Osterhaus Dean D Erdman Larry J Anderson

Human metapneumovirus (HMPV) was recently identified in The Netherlands and was linked to acute respiratory tract illness. In this study, 11 isolates from 10 patients with respiratory disease from Quebec, Canada, were tested by a reverse-transcriptase polymerase chain reaction based on the fusion protein gene. Identified sequences were consistent with HMPV. The patients were 2 months to 87 year...

Journal: :Clinical Pediatrics: Open Access 2017

Journal: :Journal of clinical microbiology 2003
Stéphanie Côté Yacine Abed Guy Boivin

The human metapneumovirus (hMPV) is a new member of the Paramyxoviridae family associated with acute respiratory tract infections in humans. The objective of this study was to compare the sensitivity of real-time RT-PCR assays performed in a LightCycler instrument and designed to amplify the viral nucleoprotein (N), matrix (M), fusion (F), phosphoprotein (P), and polymerase (L) genes. In a firs...

Journal: :Journal of clinical microbiology 2014
Angela R Branche Edward E Walsh Maria A Formica Ann R Falsey

Respiratory tract infections (RTI) frequently cause hospital admissions among adults. Diagnostic viral reverse transcriptase PCR (RT-PCR) of nose and throat swabs (NTS) is useful for patient care by informing antiviral use and appropriate isolation. However, automated RT-PCR systems are not amenable to utilizing sputum due to its viscosity. We evaluated a simple method of processing sputum samp...

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