نتایج جستجو برای: metabonomic
تعداد نتایج: 430 فیلتر نتایج به سال:
As nanoparticles could form aggregates in biological systems, the dynamics of their dispersity drives the temporal effect of nanoparticles in vitro. To test this hypothesis, the fumed silica nanoparticles (SiNPs) that have primary sizes of 7-14 nm and form aggregates in culture medium were selected for toxicity study in human lung A549 cells. The dispersity of SiNPs was analyzed by dynamic ligh...
BACKGROUND Venlafaxine is a new antidepressant that has a chemical structure and neuropharmacologic profile distinct from those of existing antidepressants. The studies about the mechanism of pharmacological action of venlafaxine mostly investigated the effects of venlafaxine on 5-hydroxytryptamine (5-HT), norepinephrine (NE) and dopamine (DA) levels, while only few studies examined the effects...
Contamination of nitrosamine compounds in Chinese sausages and the relevant hepatoxicity have been reported. This study was conducted to evaluate effects vitamin C (VC) supplementation on sausage contaminated with N-nitrosodimethylamine (NDMA)-induced liver damage metabolomic changes. Rats were orally administered NDMA at levels overpassing its safety limit. In some experiments, VC additionally...
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