نتایج جستجو برای: metabolites in serum
تعداد نتایج: 17014199 فیلتر نتایج به سال:
A relationship between formation of methylsulfonyl (MeSO2) metabolites of 2,2',4,5,5'-pentachlorobiphenyl (PentaCB) and decrease in serum thyroxine (T4) level was examined in the rats and mice after a single i.p. injection of PentaCB (342 micromol/kg body weight). In either rats or mice, levels of the 3- and 4-MeSO2 metabolites of PentaCB in the liver and feces increased in a time-dependent fas...
Oral squamous cell carcinoma is an important malignancy of epithelial origin with high rate of morbidity and mortality. While tobacco and alcohol are the primary risk factors; other factors such as microorganisms, chronic irritation and sex hormones along with underlying genetic factors may also contribute to its pathogenesis. The role of sex hormones like estrogen, progesterone and testosteron...
Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological pathways and help to identify individuals at risk for disease. We prospectively investigated the association between serum metabolites measured by targeted metabolomics and risk of T2D in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam (27,548 adults) among all incident cases...
normal 0 false false false en-us x-none fa microsoftinternetexplorer4 aim : the aim of this study is to look for the proper methods that would be a major step towards untreated cd diagnosis and seek the metabolic biomarkers causes of cd and compare them to control group. background : celiac disease (cd) is a common autoimmune disorder that is not easily diagnosed using the clinical tests. patie...
Abstract Purpose The relationship between Hashimoto's thyroiditis and vitamin D concentration was already presented in many studies. aim of this study to analyze the differences metabolites healthy women with (HT). Methods quantitative analysis five carried out using liquid chromatography coupled tandem mass spectrometry. analyzed materials were serum dried blood spots (DBS). results obtained f...
Metabolite differences between sexes have rarely been observed in a global manner, but it has recently been made possible by the advancement in metabolomics techniques. In this study, untargeted ultraperformance liquid chromatography coupled to time-of-flight mass spectrometry and an in-house software platform were used for a rapid comparison of sex differences in urinary metabolites in humans ...
OBJECTIVE Patients with type 1 diabetes (T1D) with impaired renal function are at increased risk for end-stage renal disease (ESRD). Although the rate of progression varies, determinants and mechanisms of this variation are unknown. RESEARCH DESIGN AND METHODS We examined serum metabolomic profiles associated with variation in renal function decline in participants with T1D (the Joslin Kidney...
The present study was conducted to evaluate the effect of L-carnitine supplementation accompanied with two sources of fat supplemented diets (ω3 and ω6) on flushing period of Farahani ewes. 20 Farahani ewes were allocated in four different treatments which were as follow: 1) 2.5% dry matter intake ω3 source without L-carnitine 2) 2.5% dry matter intake ω6 source without L-carnitine 3) 2.5% dry ...
An experiment was conducted to determine the effect of different levels of potato replacing maizeseed on performance characteristicsand immunes system of broiler chicken in a completely randomized design. A total of 220 broiler chicks were randomly assigned to 5 treatment groups, with 4 replicates of 11 birds each. The chicks in the first group were fed basal diet (control), 2nd and 3rd groups ...
Medicinal plants have curative properties due to the presence of various complex chemical compositions, which are found as secondary plant metabolites in one or more parts of the plant. The aim of this study was to compute the antidiabetic activity of Holarrhena antidysenterica seeds extract in streptozotocin-induced diabetic rats. The experimental protocol designed as animals were divided i...
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