Excess body weight (adiposity) and physical inactivity are increasingly being recognized as major nutritional risk factors for cancer, and especially for many of those cancer types that have increased incidence rates in affluent, industrialized parts of the world. In this review, an overview is presented of some key biological mechanisms that may provide important metabolic links between nutrit...

Background: The risk of disease with 1 risk factor is increased by the presence of additional risk factors. The goal of this study was to assess the prevalence of multiple coronary artery disease (CAD) risk factors among adults in Kerman, Iran, to identify the population groups most at risk.Methods: The present study included 5900 adults aged between 15 and 75 years in 2011 in Kerman, Iran. The...

OBJECTIVES To discuss the metabolic syndrome and identify its risk factors, including in the pediatric age group. SOURCES Indexed review articles. SUMMARY OF THE FINDINGS The metabolic syndrome is characterized by insulin resistance and the presence of risk factors for cardiovascular diseases and diabetes mellitus type 2. Consensus has not yet been reached on its diagnostic criteria. This r...

BACKGROUND Associations of serum calcium levels with the metabolic syndrome and other novel cardio-metabolic risk factors not classically included in the metabolic syndrome, such as those involved in oxidative stress, are largely unexplored. We analyzed the association of albumin-corrected serum calcium levels with conventional and non-conventional cardio-metabolic risk factors in a general adu...

2005;46;2054-2060; originally published online Nov 8, 2005; J. Am. Coll. Cardiol. Lars Lind Erik Ingelsson, Johan Ärnlöv, Johan Sundström, Björn Zethelius, Bengt Vessby, and Novel Metabolic Risk Factors for Heart Failure This information is current as of January 23, 2010 http://content.onlinejacc.org/cgi/content/full/46/11/2054 located on the World Wide Web at: The online version of this articl...

OBJECTIVES Our objectives were to explore novel metabolic risk factors for development of heart failure (HF). BACKGROUND In the past decade, considerable knowledge has been gained from limited samples regarding novel risk factors for HF, but the importance of these in the general population is largely unexplored. METHODS In a community-based prospective study of 2,321 middle-aged men free f...

RESEARCH DESIGN AND METHODS — Men and women (55%) aged 18–30 years from the Coronary Artery Risk Development in Young Adults (CARDIA) study without the metabolic syndrome at baseline (n 4,192, 49% black) were followed-up from 1985 to 2001. Incident metabolic syndrome, defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria, was ascertained 7, 10, and 1...