amebloblastoma as the most common epithelial odontogenic neoplasm may occur in two forms of central and peripheral. this report presents a case of a 41-year-old iranian female with a six-month complaint from a painless mass in the right posterior portion of the mandible. the case was diagnosed as an exophytic epulis-like peripheral component with characteristics of peripheral ameloblastoma and ...

Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. The central effects including GH secretion, food intake, and energy homeostasis are partly mediated by Kiss1- KissR signaling pathway. Ghrelin and its receptor are also expressed in the pancreatic islets. Ghrelin is one of the key metabolic factors controlling insulin secretion from t...

AIMS To study the association between peripheral blood metabolic and inflammatory factors and presence of diabetic macular edema (DME) and its related anatomic features in type 2 diabetic mellitus (T2DM) patients. MATERIAL AND METHODS Observational cross-sectional study on a proof of concept basis. Seventy-six T2DM included patients were divided based on the presence (n = 58) or absence of DM...

The anorexia-cachexia syndrome is a debilitating clinical condition characterizing the course of chronic diseases, which heavily impacts on patients' morbidity and quality of life, ultimately accelerating death. The pathogenesis is multifactorial and reflects the complexity and redundancy of the mechanisms controlling energy homeostasis under physiological conditions. Accumulating evidence indi...

The modular biology is supposed to be a bridge from the molecular to the systems biology. Using a new approach, it is shown here that the protein interaction networks of yeast Saccharomyces cerevisiae and bacteria Escherichia coli consist of two large-scale modularity layers, central and peripheral, separated by a zone of depressed modularity. This finding based on the analysis of network topol...

various extracts of sarcostemma viminale were screened for central analgesic activity by hot plate test, peripheral analgesic activity by acetic acid-induced writhings, cns depressant activity by pentobarbitone-induced sleep and locomotor activity testing methods and anthelmintic activity on the earthworms pheretima posthuma . results showed that petroleum ether and ethyl acetate extracts had g...

Antiatherogenic Effect of Peripheral Adiposity? To the Editor: Tankó et al1 observed that peripheral adiposity in elderly women may be associated with a relatively reduced risk of insulin resistance, dyslipidemia, and vascular calcification. They suggested that this benefit reflects an antiatherogenic effect of peripheral fat. However, we believe their findings support the concept that subtly i...

Regulation of energy metabolism is controlled by the brain, in which key central neuronal circuits process a variety of information reflecting nutritional state. Special sensory and gastrointestinal afferent neural signals, along with blood-borne metabolic signals, impinge on parallel central autonomic circuits located in the brainstem and hypothalamus to signal changes in metabolic balance. Sp...

The suprachiasmatic nucleus (SCN) in the mammalian hypothalamus functions as an endogenous pacemaker that generates and maintains circadian rhythms throughout the body. Next to this central clock, peripheral oscillators exist in almost all mammalian tissues. Whereas the SCN is mainly entrained to the environment by light, peripheral clocks are entrained by various factors, of which feeding/fast...