Accepted 27 September 1995 An 81-year-old man, resident of a poorly ventilated, ineffectively air-conditioned inner city apartment, presented during a heat wave (environmental temperature 80°-93°F and humidity 70%-80%) with hyperthermia, confusion and dehydration. The patient had mild hypertension, depression and urinary incontinence and was taking hydrochlorothiazide/methyldopa, nortriptyline ...

Metabolic syndrome is a cluster of cardiovascular risk factors defined by the presence of abdominal obesity, glucose intolerance, hypertension and/or dyslipidemia. It is a major public health epidemic worldwide, and a known risk factor for the development of cognitive dysfunction and dementia. Several studies have demonstrated a positive association between the presence of metabolic syndrome an...

BACKGROUND This study looked at the association of cystatin-C (cys-C) with severity of metabolic syndrome in Asian Indians. METHODS Five sets of normal glucose tolerance subjects were recruited from the Chennai Urban Rural Epidemiology Study (CURES), a population-based study in southern India: 43 subjects with no metabolic risk factors, 44 subjects with one metabolic risk factor, 37 subjects ...

INTRODUCTION: Chronic methamphetamine use results in persistent neuropsychological deficits in abstinent methamphetamine dependent (AMD) subjects. We examined the hypothesis that elevated concentration of cerebral glutamate (Glu), an excitatory neurotransmitter and neurotoxin, occurs in human AMD. MATERIALS AND METHODS: We examined 40 subjects, 18 of whom were AMD, abstinent more than 3 weeks ...

melas syndrome is a mitochondrial disorder with progressive nature, because adequate treatment is not available. diagnosis of this mitochondrial disorder depends initially on clinical suspicion, which is strengthened by additional metabolic evidence of impaired oxidative metabolism such as high serum or c.s.f. lactate levels and confirmed by demonstration of mitochondrial abnormalities-in muscl...

INTRODUCTION Obstructive sleep apnea (OSA) is a well-recognized risk factor of cardiovascular disorders and is related to metabolic syndrome. The aim of this study was to evaluate the effect of BMI and AHI/RDI on metabolic disturbances in patients suspected of OSA. MATERIAL AND METHODS Ninety-nine patients referred with suspected OSA underwent standard polysomnography or limited sleep study. ...

The hemostatic balance is a complex system where the delicate equilibrium is regulated by several factors, including hormones. This review summarizes current knowledge of the effects of most frequent endocrine and metabolic diseases (such as hypothyroidism, hyperthyroidism, Cushing's syndrome, GH-related pituitary dysfunctions, pituitary prolactin-producing adenomas, polycystic ovary syndrome, ...

BACKGROUND It is unclear whether obesity unaccompanied by metabolic abnormalities is associated with increased cardiovascular disease risk across racial and ethnic subgroups. METHODS AND RESULTS We identified 14 364 postmenopausal women from the Women's Health Initiative who had data on fasting serum lipids and serum glucose and no history of cardiovascular disease or diabetes at baseline. We...

INTRODUCTION Urinary calculi in infants are relatively infrequent, but their incidence has increased in the recent decades. The aim of this study was to investigate the clinical presentation, metabolic risk factors, and urinary tract abnormalities in infants suffering from kidney calculus. MATERIALS AND METHODS A total of 152 infants were admitted between 2009 and 2012 with ultrasonography-pr...