A case of primary myelofibrosis involving lymph node and with a novel cytogenetic abnormality [del (18) (p11.2-3)] is reported. The abnormalities are identical among specimens from the lymph node, peripheral blood, and bone marrow that were analyzed years apart. Additionally, we show that the infiltrate by dysplastic megakaryocytes in the lymph node morphologically mimics a metastatic mesenchym...

Adrenal myelolipoma is a rare benign neoplasm of mesenchymal origin composed mature fatty tissue and bone marrow elements. It non-functioning tumor, usually asymptomatic commonly detected incidentally during evaluation for unrelated symptoms; hence, it referred to as an “incidentaloma”. Large myelolipomas can cause mass effects vague abdominal pain, spontaneous tumor rupture with massive hemorr...

Gastrointestinal tract (GIT) lipomas are rare, benign mesenchymal neoplasm affecting all segments of the GIT and colon is affected most frequently. Reported incidence colonic varies from 0.2% to 4.4%. Adult intussusception represents 1% bowel obstructions 5% intussuceptions. rare tumors due a gastrointestinal lipoma constitute an infrequent clinical entity. Although common disease in children, ...

Gastrointestinal stromal tumor is rare digestive tract mesenchymal tumor, most often in the wall of the stomach. It is a benign neoplasm, but it can become malignant if not treated. We report a case of gastrointestinal stromal tumor that was discovered after abdominal ultrasonography during staging of a patient with primary cutaneous amelanotic melanoma. Mutation in the tyrosine kinase receptor...

Penile cancer is an uncommon primary genitourinary malignancy, the vast majority representing superficial squamous cell carcinomas. However, less common skin cancers, secondary malignancies, mesenchymal neoplasms, and hematopoietic tumors do affect the penis. Medical history, atypical presentation, and deep epicenter of a penile mass may raise question of a nonepithelial neoplasm. We describe a...

Lipoma is a benign soft tissue tumor, composed of mature fat cells. It represents by far the most common benign mesenchymal neoplasm which can occur throughout the whole body, but it rarely originates in the abdominal wall. Due to its rare etiologic origin and obscure cause of development, we herby report on a case of a lipoma in a 45-year-old male who presented with chronic left flank pain tha...

Sarcomas of the esophagus, including carcinosarcoma, are rare neoplasm cases and comprise 0.1-1.5% of all esophageal tumors. Leiomyosarcoma is the most common of the pure mesenchymal tumors of the esophagus, but sarcomas with combined histological types such as carcinosarcoma occur more frequently than pure sarcomas. We report a rare case of spindle cell sarcoma of esophagus in a 55-year-old wo...

Primary cardiac chondrosarcoma is extremely rare with very few cases reported in the literature. Most cardiac chondrosarcomas described in the literature are secondary. We report herein a case of 22-year-old man who presented with easy fatigability, which the general practitioner diagnosed as mitral stenosis clinically. Echocardiography showed left atrial mass, possibly myxoma. The histopatholo...

A case is reported of a neoplasm of mixed mesenchymal and neuroepithelial origin consisting of plasmacytoma, lymphoma, ganglioneuroma, and astrocytoma in the same mass. The tumour arose in the hypothalamus of a 43 year old diabetic woman who also had alpha cell hyperplasia and beta cell hypoplasia of the islets of Langerhans. It is suggested that both hypothalamic and pancreatic lesions produce...

The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site.PRIMARY LEIOMYOSARCOMA OF THE ADRENAL GLAND IS A VERY RARE MALIGNANT MESENCHYMAL NEOPLASM: to our knowledge, this is only the twelfth case reported...