Through a community study of boys requiring special education for the severely mentally retarded, 12 families were ascertained in which the fragile X was found to be segregating. By assiduous follow up of these families, it was found that in only four of them could male transmission be ruled out from the grandparents' or great grandparents' generation and that the segregation ratios are disturbed.

et al., 1961; Lubs, Koenig, and Brandt, 1961) has recently been identified with the late-replicating, distally labelled, D1 (13) pair (Yunis, Hook, and Mayer, 1964b; Yunis et al., 1964a; Yunis and Hook, 1966; Gianne]li, 1965; Giannelli and Howlett, 1966; Lee et al., 1966; Wilson et al., 1967; Bloom and Gerald, 1968). This report concerns a retarded adult with some manifestations of the D1 syndr...

Recalling the principles of the Universal Declaration of Human Rights, the International Covenants on Human Rights, the Declaration of the Rights of the Child and the standards already set for social progress in the constitutions, conventions, recommendations and resolutions of the International Labour Organisation, the United Nations Educational, Scientific and Cultural Organization, the World...

Parents of 50 mentally retarded children were investigated for their attitudes towards their retarded children. Both the parents showed more negative attitudes toward their severely retarded child. In general mothers exhibited more negative attitude than the fathers.

to 0.294)Affective disorders0.0910.040(6)(—0.325 to 0.421)Adjustment disorders0.5230.298(7)(—0.067 to 0.766)Anxiety disorders0.5630.369(7)(—0.069 to 0.577)Inappropriate mental0.4040.304adjustment (7)(—0.3 12 to 0.45 1)Somatoform disorders0.6030.281(6)(0.239 to 0.556)Personality disorders0.5090.3 17(7)(—0.028 to 0.523)Factor 1: affective0.6930.342(14)(—0.273 to 0.613)Factor 2: somato...