intracerebroventricular (icv) injection of streptozotocin (stz) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic alzheimer’s disease (sad). epidemiological studies suggest that non-steroidal anti-inflammatory drugs (nsaids) could delay or slow the clinical expression of sad. therefore, the beneficial e...

in fact alcohol is a toxic substance that has a direct effect on brain. some of the most common mental disorders due to alcohol abuse are: memory disorder: hazardous amounts of alcohol may cause intoxication, impairment of memory so that the person who took a drunken accident may not remember the event. periods of memory impairment in those with a history of alcohol addiction would also happen ...

for a long time, scientists have tried to describe disorders just by genetic or environmental factors. however, the role of epigenetics in human diseases has been considered from a half of century ago. in the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

social anxiety disorder (sad) is the one of the most common anxiety disorders. despite its high prevalence, the disorder is still considerably undiagnosed and untreated. the disease places a massive burden on patient’s lives, affecting not only their social interactions but also their educational and professional activities, thereby constituting a severe disability. γ-aminobutyric acid (gaba) s...

BACKGROUND Some studies have shown the presence of psychopathological disorders in transient global amnesia. AIMS To determine whether transient global amnesia is associated with psychopathological disorders and to assess the influence of these psychopathological disorders on memory impairments. METHOD Levels of anxiety and depression before and during transient global amnesia were rated. M...

In a previous study, we investigated the relationship between the disorders of both episodic memory and working memory in the acute phase of transient global amnesia (TGA). Since executive functions were spared, another dysfunction may be responsible for the binding and maintenance of multimodal informations and contribute to the encoding disorders observed in some patients [Quinette, P., Guill...