Abstract Background Pigmented epithelioid melanocytomas (PEMs) pose a challenge in terms of diagnosis and management, this is due to the wide spectrum disease severity. Not only management grey area, but there controversy over follow up, their indeterminate malignant potential. Case An 11-year-old boy presented with six-month history rapidly changing pigmented naevus on his upper back. He had F...

Neurocutaneous melanosis (NCM) is a rare condition characterized by central nervous system melanocytic tumors associated with congenital melanocytic nevi. Phacomatosis pigmentovascularis (PPV) is an association of vascular nevus with pigmentary nevus. Aberrant maturation of neural crest-derived cells is considered to be related to pathogenesis in both conditions. However, association of NCM and...

Meningeal melanocytoma is a kind of extremely rare pigmented tumor of the central nervous system, which often occurs in the groove around the base of the brain and spinal pia mater. Age of onset is 40 to 50 years old, mostly presenting a benign course of disease and the prognosis is good. Case reports of partial invasion or metastasis from lesions are even rarer. This report described a case of...

as a medical device by the Food and Drug Administration in the United States. This enzymatic cleaner is “generally regarded as safe” by the Food and Drug Administration and the European Medical Evaluation Agency. Nevertheless, serious adverse ocular effects frequently do not come to the attention of government regulators until a product is marketed to the public, owing to the limited number of ...