www.thelancet.com/neurology Vol 8 January 2009 19 as chemoradiation add to the burden of disease. In a randomised EORTC study in 386 patients with anaplastic oligodendrogliomas, the eff ect of combined procarbazine, lomustine, and vincristine (PCV) chemotherapy after radiotherapy was compared with radiotherapy. Quality of life was measured using EORTC questionnaires on quality of life and on br...

First, the authors did not hypothesize that sex may modify the association between ABO blood type and ARDS risk. Previous studies found that women were more likely to develop ARDS compared with men, 2 whereas sex is not associated with ABO blood type distribution. Th us, it might be reasonable to hypothesize that the eff ects of ABO blood type on ARDS diff er between men and women. Because the...

E. Jaba, A. Morosanu, Alexandru Ioan Cuza University, Iaşi, D. Şerban, M. Gruiescu, Academy of Economic Studies Bucharest, Romania This paper presents some solutions to recruit staff for the Marketing Department of a metallurgical enterprise. Our goal is to present the psychological characteristics of a certain category of employees on a sample of 107 employees and to evaluate the relationship ...

We read with interest the Point and Counterpoint editorials in CHEST (May 2014) by Suissa and Rabe 1 and Rho et al 2 about the appropriateness of industry-sponsored rofl umilast trials. In the editorials, reference was made to the level of patient withdrawal as well as to the level of side eff ects experienced by patients receiving this drug during clinical trials. 2 In our real-world clinical ...

We analyze the eff ect of job insecurity on psychological health. We extend the group of people being aff ected to employees who have insecure jobs to account for a broader measure of the mental health consequences of potential unemployment. Using panel data with staff reductions in the company as an exogenous source of job insecurity, we fi nd that an increase in fear of unemployment substanti...

Foxp3(+) CD25(+)CD4(+) regulatory T (Treg) cells are crucial for the maintenance of immunological self-tolerance and are abundant in tumors. Most of these cells are chemo-attracted to tumor tissues and suppress anti-tumor responses inside the tumor. Currently, several cancer immunotherapies targeting Treg cells are being clinically tested. Cisplatin is one of the most potent chemotherapy drugs ...

Background Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all women with node-positive disease considered together. However, the benefi t in women with only one to three positive lymph nodes is uncertain. We aimed to assess the eff ect of radiotherapy in these women after mastectomy and axillary dissection.

Tobacco control policies have proliferated in many countries in recent years, in particular youth access laws and public smoking bans. The eff ectiveness of youth access laws is still disputed, however, as are the costs of public smoking bans to the hospitality industry. Using a unique data set on cigarette sales at more than 100k vending machines that provides fi rst objective evidence on the ...

A number of recent empirical studies document signifi cant eff ects of in-patient care quality indicators on the choice of hospital. These studies use either objective quality indicators based on quantitative fi gures, or if subjective reputation scores are used, scores based on the opinion of hospital market insiders. We contribute to the current debate by using a subjective reputation score r...

Peter Kokkinos and colleagues (Feb 2, p 394) describe the interactive eff ects of fi tness and statins on mortality risk in veterans with dyslipidaemia. They report that increasing physical activity and statins independently lowers lipid levels and total mortality, but that the combination of these interventions is superior to either alone. The authors conclude that prescription of physical act...