in this paper, the quantitative structure activity-relationship (qsar) of the ccr2b receptor inhibitors was scrutinized. firstly, the molecular descriptors were calculated using the dragon package. then, the stepwise multiple linear regressions (sw-mlr) and the genetic algorithm multiple linear regressions (ga-mlr) variable selection methods were subsequently employed to select and implement th...

the recent years have witnessed an increasing attention to the methods of multiple attribute decision making in solving the problems of the real world due to their shorter time of calculation and easy application. one of these methods is the ‘permutation method’ which has a strong logic in connection with ranking issues, but when the number of alternatives increases, solving problems through th...

a robust and reliable quantitative structure-property relationship (qspr) study was established to forecast the melting points (mps)  of a diverse and long set including 250 drug-like compounds. based on the calculated descriptors by dragon software package, to detect homogeneities and to split the whole dataset into training and test sets, a principal component analysis (pca) approach was used...

Endoscopic radial artery harvesting (ERAH) is a feasible and attractive minimally invasive approach for conduit procurement, however there have been concerns about a potential neurological damage occurring at the harvest limb site secondary to injury of the radial nerve during endoscopic harvesting. We present a case of ERAH in which we evaluated intraoperatively the characteristics of radial n...

K-means (MacQueen, 1967) [1] is one of the simplest unsupervised learning algorithms that solve the well-known clustering problem. The procedure follows a simple and easy way to classify a given data set to a predefined, say K number of clusters. Determination of K is a difficult job and it is not known that which value of K can partition the objects as per our intuition. To overcome this probl...

Invasive grass weeds reduce farm productivity, threaten biodiversity, and increase weed control costs. Identification of invasive grasses from native grasses has generally relied on the morphological examination of grass floral material. DNA barcoding may provide an alternative means to identify co-occurring native and invasive grasses, particularly during early growth stages when floral charac...

This paper presents a generalized version of the conventional k-means clustering algorithm [Proceedings of 5th Berkeley Symposium on Mathematical Statistics and Probability, 1, University of California Press, Berkeley, 1967, p. 281]. Not only is this new one applicable to ellipse-shaped data clusters without dead-unit problem, but also performs correct clustering without pre-assigning the exact...

In this paper we present a new clustering method based on k-means that has been implemented on a video surveillance system. Rekmeans does not require to specify in advance the number of clusters to search for and is more precise than k-means in clustering data coming from multiple Gaussian distributions with different co-variances, while maintaining real-time performance. Experiments on real an...