Objective: To evaluate the gastroprotective effects of β 3 -adrenoceptor agonists CGP 12177A and SR 58611A, on water immersion plus restraint stress (WIRS)-induced gastric ulceration in rats. Material and Methods: Drugs were administered (5, 10 and 15 mg/kg, p.o. ) 30 min prior to the ulcerogenic procedure. Ulcer index and the score for intensity of intraluminal bleeding were determined. Gastri...

Although, over the past few years, the application of mammography has risen up sharply in Iran, very little, if any, has been reported of the extent of patient's dose from this type of imaging. The purpose of this study was to establish local diagnostic reference level (DRL) arising from mammography in the great Khorasan province of Iran. It is generally assumed that the glandular tissue is the...

Mammography, using X-rays, is routinely utilized for screening of patients for prevention of breast cancer. Nevertheless, there is a small but significant risk of radiation induced carcinogenenesis associated with radiation exposure of the breast, being glandular tissue the most sensitive one among the tissues composing breast. Risk estimation in mammography may be determined by the mean absorb...

BACKGROUND Resectional breast surgery has become less extensive. Dissection on plane of the superficial fascia covering the breast (juxtacapsular) is used during various procedures for retention of the appearance of the breast. The accuracy of this method and its ability to remove all glandular breast tissue has never been tested. METHODS Twenty patients with breast cancer were studied prospe...

OBJECTIVES To assess the clinical significance of a cervical cytological diagnosis of atypical glandular cells of undetermined significance and to formulate the most appropriate management guidelines for patients with such a diagnosis. DESIGN Retrospective study. SETTING Regional hospital, Hong Kong. PATIENTS Seventy-two patients with diagnoses of atypical glandular cells of undetermined ...

INTRODUCTION Many physiological changes of breast elasticity depend on the age, hormonal status, menstrual cycle and many others. The aim of this study was to evaluate viscoelastic properties of normal breast tissues in a large group of women and to search for factors which play a role in its mechanical properties. MATERIAL AND METHODS 101 women aged 18-74 years who underwent B-mode sonograph...

Methyleugenol (MEG) was tested for toxicity/carcinogenicity in a 2-yr carcinogenesis bioassay because of its widespread use in a variety of foods, beverages, and cosmetics as well as its structural resemblance to the known carcinogen safrole. F344/N rats and B6C3F(1) mice (50 animals/sex/dose group) were given MEG suspended in 0.5% methylcellulose by gavage at doses of 37, 75, or 150 mg/kg/day ...

For the dose study, a semi-automated method of data collection is used in this study. The participating centres were asked to fill out a spreadsheet with all necessary data and return it. For direct digital (DR) systems, the relevant data available in the DICOM header were used. All data is automatically added to a database and processed. The data were used to calculate the mean glandular dose ...