ACKNOWLEDGEMENTS The medical case histories referred to are the original MS records now bound in one volume and filed in the hospital on the island. For background information the literature is very meagre, but I have had recourse to the following: St. Helena by Philip Gosse, (London, Cassell, 1938); Six Months on Ascension by Mrs. Gill (London, John Mufray); Darwin and The Beagle, by Alan Moor...

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Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and results in significant morbidity and mortality. The left atrial appendage (LAA), a small embryonic remnant of the left atrium (LA), has been shown to play a key role in the pathophysiology of AF-related stroke and thromboembolism. As a consequence the LAA, in spite of its meagre size, has been described as ‘our most leth...

Flowering is of prime importance in plant’s life and in breeding, which determines generation turn over and genetic gain. It has been established that the flowering is under genetic control but highly influenced by the environmental factors. The quantum of flowering and pollen production is inconsistent, abundant in some years and meagre or absent in others at individual and community level, af...

Background Diabetic patients at high risk for foot ulceration are often prescribed with custom-made therapeutic footwear. However, the evidence base to support the use of this footwear for ulcer prevention is still meagre [1]. The lack of offloading efficacy may play a role in this. In-shoe plantar pressure assessment is a valuable tool for evaluating footwear and guiding modifications to optim...

Every 18 seconds someone, somewhere is infected with HIV. The scale of the epidemic has not been exaggerated. On average, HIV-infected individuals have their immune system destroyed by this virus over a 9 year period, resulting in the acquisition after that time of an immune deficiency state (AIDS). Once defenceless, many organisms may seize upon the opportunity presented and infect an unresist...

subject. The style is concise; but reads more like a student's note-book than a finished literary work. The diagrams are excellent, some parts of the subject are fairly completely dealt with ; but, the account of the Histology of the nervous system is very meagre and the diagrams few. The chapter on Technique is not sufficiently comprehensive and no mention is made of frozen sections of fresh t...

Very little attention has been paid to the invisible epidemic of substance misuse among older people in the UK. This article looks at the prevalence of substance misuse in the people over the age of 60. The reasons for difficulty in diagnosing substance misuse are explored and ways to improve diagnostic ability are discussed. Substance misuse leads to severe physical and psychiatric morbidity t...

and Bricon. Translated from the Second Edition, with Additions by Andrew S. Currie, M.D. London: H. K. Lewis. 1887. Dr. Currie has done good service in giving us a translation of this book, as it is most desirable that English readers should be made familiar with foreign works, that have been well received in their own country. There is first a most meagre history of the hypodermic method and a...

Human impacts on marine ecosystems are increasing and the number of fish species listed in Red List is constantly growing. In Mediterranean Sea, seven 10 bony fishes defined as Threatened by IUCN known to be vocal, including target this study: shi drum (Umbrina cirrosa Linnaeus, 1758) brown meagre (Sciaena umbra 1758). As a result, non-invasive passive acoustic monitoring (PAM) can used pinpoin...