Vasculogenic mimicry (VM) is a vascular-like structure which can mimic the embryonic vascular network pattern to nourish the tumour tissue. As a unique perfusion way, VM is correlated with tumour progression, invasion, metastasis and lower 5-year survival rate. Notably, epithelial-mesenchymal transition (EMT) regulators and EMT-related transcription factors are highly up-regulated in VM-forming...

Cloud computing is a computing advancement that provides a large number of computing and storage resources to different people. Management of huge amount of data in cloud computing is done by VM consolidation. Nowadays, energy saving has become a key aspect in designing VM consolidation algorithms. Algorithms for selecting next VM have never given consideration to both power and data at the sam...

Virtual Machine (VM) Consolidation contributed a lot in energy efficient computing in the cloud data centers. Virtualization played a great role in virtual machine consolidation by facilitating the live VMs to be migrated resulting in packing the maximum number of VMs in minimum possible physical hosts .Energy efficient computing is not only good for reducing the overall operational cost of the...

Vasculogenic mimicry (VM) refers to the condition in which tumour cells mimic endothelial cells to form extracellular matrix-rich tubular channels. VM is more extensive in more aggressive tumours. The human epidermal growth factor receptor 2 (HER2) gene is amplified in 20-30% of human breast cancers and has been implicated in mediating aggressive tumour growth and metastasis. However, thus far,...

Allometric scaling is one of the most pervasive laws in biology. Its origin, however, is still a matter of dispute. Recent studies have established that maximum metabolic rate scales with an exponent larger than that found for basal metabolism. This unpredicted result sets a challenge that can decide which of the concurrent hypotheses is the correct theory. Here we show that both scaling laws c...

The utilization of cloud data centres in combination with Virtualization technology has advantages of running more than one virtual machine in a single server. The data centres are a collection of many servers, allocation of VM to Host is known as VM placement. VM placement problem was examined in this paper with focus for maximum utilization of the resources and energy reduction. Switching off...

Variations in the technique of the Valsalva manoeuvre (VM) have been shown to greatly influence the pattern of cardiovascular response (CVR) to the test. Intra-strain tachycardia, post-strain bradycardia, Valsalva ratio, and baroreflex sensitivity decrease in proportion to an increase in lung volume and a decrease in strain pressure at VM. In conditions of completely expanded lungs and low stra...