INTRODUCTION Alzheimer's disease (AD), the leading cause of dementia, is pathologically characterized by β-amyloid plaques and tau tangles. However, there is also evidence of lipid dyshomeostasis-mediated AD pathology. Given the structural diversity of lipids, mass spectrometry is a useful tool for studying lipid changes in AD. Although there have been a few studies investigating lipid changes ...

BACKGROUND Reduced hippocampal volume in schizophrenia is a well-replicated finding. New imaging techniques allow delineation of hippocampal subfield volumes. Studies including predominantly chronic patients demonstrate differences between subfields in sensitivity to illness, and in associations with clinical features. We carried out a cross-sectional and longitudinal study of first episode, su...

Theorem 1. Let K = 〈K,+, ·, . . .〉 be an expansion of K all of whose atomic relations are definable in R. If K is a proper expansion of 〈K,+, ·〉 then the field R is definable in K. By “proper expansion of 〈K,+, ·〉”, we mean that there is a definable set in K which is not definable in 〈K,+, ·〉 (even with parameters). In particular, the theorem implies that there are no proper expansions of an al...

We investigated maximal Prym varieties on finite fields by attaining their upper bounds on the number of rational points. This concept gave us a motivation for defining a generalized definition of maximal curves i.e. maximal morphisms. By MAGMA, we give some non-trivial examples of maximal morphisms that results in non-trivial examples of maximal Prym varieties.

We propose the notion of the crystalline sub-representation functor defined on p-adic representations of the Galois groups of finite extensions of Qp, with certain restrictions in the case of integral representations. By studying its rightderived functors, we find a natural extension of a formula of Grothendieck expressing the group of connected components of a Neron model of an abelian variety...

Reply by Moyer: Pamela Fitch makes good points in response to my recent editorial on affective massage therapy (AMT), and I recall that when I was writing it, I wavered on whether to nominate AMT only as a subfield for research or as a subfield for research and practice. I also had, in addition to Fitch’s letter, a thought-provoking email exchange on that topic with Dr. Lesley Teitelbaum. Limit...

Purpose: We demonstrate that meaningful cross-sectional differences in the subfields of the hippocampal formation (HF) can be detected in patients with mild cognitive impairment (MCI) using automatic segmentation of focal T2-weighted MRI. Boundaries between the layers and subfields of the HF are virtually indistinguishable in routine 1 mm T1-weighted MRI at 1.5 and 3 Tesla. However, mounting ev...

This research-in-progress paper reports bibliometric characteristics that illustrate and give credence to the claim of the Nobel Prize committee that its 2012 Nobel Prize in Physiology or Medicine was awarded for a “paradigm shift”. An all-author co-citation analysis (ACA) of stem cells research 2004-2009 provides an interesting characterization of this paradigm shift, which was triggered by a ...