Oncolytic adenoviral vectors that express immunostimulatory transgenes are currently being evaluated in clinic. Preclinical testing of these vectors has thus far been limited to immunodeficient xenograft tumor models since human adenoviruses do not replicate effectively in murine tumor cells. The effect of the immunostimulatory transgene on overall virus potency can therefore not be readily ass...

The flight of birds or insects has fascinated scholars and physicists for many centuries. Flapping motion, as shown by many nature flyers, is the most efficient way of flying objects whose size are smaller than or around 6 inches. In this chapter, the author introduced how to use modern technology to fabricate the flapping wings for micro aerial vehicles (MAVs) with flexibility and smartness. T...

Purpose – The purpose of this paper is to present a localisation system for an indoor rotary-wing micro aerial vehicle (MAV) that uses three onboard LEDs and base station mounted active vision unit. Design/methodology/approach – A pair of blade mounted cyan LEDs and a tail mounted red LED are used as on-board landmarks. A base station tracks the landmarks and estimates the pose of the MAV in re...

Rapid prototyping environments can speed up the research of visual control algorithms. We have designed and implemented a software framework for fast prototyping of visual control algorithms for Micro Aerial Vehicles (MAV). We have applied a combination of a proxy-based network communication architecture and a custom Application Programming Interface. This allows multiple experimental configura...

In this work, an autonomous micro-aerial vehicle (MAV) system prototype is presented, which is specifically designed for controlled mobility in disaster communication networks. Our requirements and our motivation for designing and building such a system differ from traditional approaches both in hardware and software aspects , as rapid MAV system prototyping is a crucial asset for us. Our syste...

The problem of developing a reliable system for sensing and controlling the hover of a Micro Air Vehicle (MAV) using visual snapshots is considered. The current problem is part of a larger project, which is developing an autonomous MAV, controlled by vision only information. A new algorithm is proposed that uses a stored image of the ground, a snapshot taken of the ground directly under the MAV...

It has been proposed that adenoviruses establish and maintain persistent infections by reducing the class I major histocompatibility complex-associated presentation of viral antigens to cytotoxic T lymphocytes, leading to ineffective cell-mediated immunity and impaired clearance of infected cells (W.S.M. Wold and L. R. Gooding, Virology 184:1-8, 1991). Early region 3 of human adenovirus types 2...

Environmental contamination of arsenic (As) and its accumulation in rice (Oryza sativa L.) is of serious human health concern. In planta speciation of As is an important tool to understand As metabolism in plants. In the present study, we investigated root to shoot As translocation and speciation in rice exposed to inorganic and methylated As. Arsenate (AsV) and methylarsonate (MAV) were effici...

Respiratory viruses cause substantial disease and are a significant healthcare burden. Virus-induced inflammation can be detrimental to the host, causing symptoms during acute infection and leading to damage that contributes to long-term residual lung disease. Prostaglandin E2 (PGE2) is a lipid mediator that is increased in response to many viral infections, and inhibition of PGE2 production du...

Advanced and accurate modelling of a Flapping Wing Micro Air Vehicle (FW MAV) and its control is one of the recent research topics related to the field of autonomous Unmanned Aerial Vehicles (UAVs). In this work, a four wing Natureinspired (NI) FW MAV is modeled and controlled inspiring by its advanced features like quick flight, vertical take-off and landing, hovering, and fast turn, and enhan...