The hair follicle undergoes a lifelong developmental cycle that depends on the integration between activating and inhibitory signals acting to regulate and guide the proliferation and differentiation of pluripotent epithelial stem cells. The effectors and mechanisms responsible for re-entry of quiescent telogen hair follicles into the hair-producing anagen stage in mature skin remain incomplete...

Andrew Francis Dixon studied human anatomy and egg [2] cells at the turn of the twentieth century in Ireland and Great Britain. Dixon studied the sensory and motor nervous system of the face, the cancellous bone tissue of the femur, supernumerary kidneys, and the urogenital system. In 1927 Dixon described a mature human ovarian follicle. This follicle, Dixon noted, contained an immature human e...

background: the purpose of this study was to evaluate the effect of needle type on pain and bleeding during oocyte pick-up (opu). methods: from may through november 2013, patients undergoing opu from a single follicle without any analgesic treatment were including this study. eligible patients (n=75) were randomized 1:1 to undergo the procedure with either a reduced needle (17 gauge body, 20 ga...

Abstract Background The gene expression of anti-Mullerian hormone receptor type 2 ( AMHR2 ) and follicle stimulating (FSHR) in cumulus cells (CCs) isolated from mature immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity quality. CCs 100 infertile women with different etiologic factors were subdivided into control (CCs MII) case GV) group. Q-PCR used ...

BACKGROUND The mammalian ovary is controlled by a number of biological rhythms, which regulate the recruitment and release of mature oocytes. The main objective of this study was to investigate the role of cellular clock proteins during follicle maturation in the mouse estrous ovary. METHODS Immunohistochemical (IHC) studies were performed on ovaries from 50 estrous staged mice culled at two ...

background: ovarian tissue transplantation is emerging technologies for fertility preservation. in addition, in vitro maturation (ivm) of oocytes retrieved from ovarian tissues may overcome the fertility defects in certain cases. objective: the aim was to evaluate the best site for ovarian tissue transplantation in mice. also, feasibility of ivm of oocytes retrieved from auto grafted ovarian ti...

background: based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (fsh) and luteinizing hormone (lh) put on their main effects on the granulosa and theca cells. lh is essential for androgens production. androgens are used for estradiol production by granulosa cells. profound suppression of lh concentrations in some normogonadotropic patients can cau...

This study was conducted to examine follicle growth and intra-ovarian oocyte release in rabbit ovaries influenced by a local application of prostaglandin formation inhibitors. While five rabbits remained as unstimulated controls, twenty-seven mature rabbits were hyperstimulated by pure follicle stimulating hormone (FSH) followed by human chorionic gonadotropin (hCG) at time 0. At the same time,...

OBJECTIVE To determine some major characteristic differences between two consecutive successful and unsuccessful intracytoplasmic sperm injection (ICSI) cycles in poor responders. MATERIALS AND METHODS Sixty women with poor ovarian response as determined using the Bologna criteria underwent ICSI cycles following an unsuccessful trial. Some parameters of both cycles including age, body mass in...