BACKGROUND Maternal death reviews and obstetric audits identify causes and circumstances related to occurrence of a maternal death or serious complication and inform improvements in quality of care. Given Nigeria's high maternal mortality, the lessons learned from past experiences can provide a good evidence base for informed decision making. We aimed to synthesise findings from maternal death ...

A preterm male infant born at 33 weeks of gestation developed respiratory depression and apnea at approximately 20 h after birth. Laboratory tests indicated severe hypermagnesemia, acidosis, and hypercalcemia. Cord blood and maternal blood concentrations of magnesium were normal. The effects and possible causes of hypermagnesemia are reviewed. The infant recovered with treatment, although the e...

Practice Pointers Preterm birth, defined as occurring before 37 weeks of gestation, is the leading cause of neonatal death and is associated with several shortand long-term infant morbidities. Tocolytics, agents that inhibit uterine contractions, are commonly used to prevent or delay preterm birth. Magnesium sulfate is one of the most commonly used tocolytics in the United States.1 An earlier p...

INTRODUCTION The optimal dosing regimen of magnesium sulfate for treating preeclampsia and eclampsia is unclear. Evidence from the Cochrane review of randomized controlled trials (RCTs) was inconclusive due to lack of relevant data. MATERIAL AND METHODS To complement the evidence from the Cochrane review, we assessed available data from non-randomized studies on the comparative efficacy and s...

This cross sectional record based institutional study was conducted in the Department of Obstetrics & Gynaecology, Burdwan Medical College, Burdwan over ten years (1999-2008) aiming analysis of eclamptic mothers for evaluation of maternal and perinatal outcome with different anticonvulsant medications. Total 5991 pregnant mothers with eclampsia admitted in the inpatient department of the tertia...

STUDY OBJECTIVE To examine the association between maternal diet in pregnancy and offspring height, sitting height, and leg length. DESIGN Cohort study. SETTING South west England. PARTICIPANTS 6663 singletons (51% male) enrolled in the Avon longitudinal study of parents and children, with information on their mother's diet in late pregnancy (obtained by food frequency questionnaire) and ...

PATH, an international nonprofit organization, assessed nearly 40 technologies for their potential to reduce maternal mortality from postpartum hemorrhage and preeclampsia and eclampsia in low-resource settings. The evaluation used a new Excel-based prioritization tool covering 22 criteria developed by PATH, the Maternal and Neonatal Directed Assessment of Technology (MANDATE) model, and consul...

Preeclampsia is a multisystem disorder which still the leading cause of maternal death today. The occurrence seizures in preeclampsia (eclampsia) increases risk and perinatal morbidity mortality. Therefore, seizure should be prevented managed accurateely.The standard therapy for managing severe preeclampsia/eclampsia use an anticonvulsant that aimed to prevent/stop seizures, prevent recurrence ...

BACKGROUND Eclampsia manifests as seizures and is unique to the pregnant state. It remains an important cause of maternal mortality especially in resource-challenged countries that lack access to prenatal care. AIMS The aim of our study was to compare maternal and foetal outcomes in mothers with eclampsia with the administration of either magnesium sulphate or phenytoin in a resource- challen...

In the past, reluctance to determine the serum magnesium level in the newborn infant has been due in part to the relative unreliability of methods hitherto employed (Wacker and Vallee, 1958), and the need for large amounts of blood, particularly where repeat determinations are proposed. In 1964 Rice and Lapara described a rapid, accurate ultramicro method for the determination of ionic magnesiu...