A series of mannich bases (3a-3j) were synthesized by the reaction of 4-[2-methyl-4-oxo-4H-quinazolin-3-yl] benzoic acid (2) with formaldehyde and appropriate amines by conventional technique. The procedure afforded various quinazolinone derivatives with 75% yield. Structures were characterized by means of spectral data. All the synthesized compounds were subjected to biological evaluation for ...

Some new Mannich Bases of 1, 4 Dihydropyridine derivatives were synthesised by reaction of 1, 4 Dihydropyridine derivatives formaldehyde (HCHO) & secondary amines (e.g. morpholine, 1-methyl piperazine) in 1:1 ratio under acidic condition in presence of trace HCl. The compounds synthesised were identified by UV, 1H NMR, and FT-IR spectroscopic techniques. All compounds studied in this work were ...