The present investigation was undertaken because of the need for a more practicable procedure for isolating pure porphyrins from biological materials. The existing methods, based primarily on solvent fractionation, on adsorption chromatography with calcium carbonate, talc, aluminum oxide, or other adsorbents, or on a combination of the two procedures, have failed in our hands to give an entirel...

1 . Thin-layer chromatography of porphyrin methyl esters provides a useful and rapid technique for resolving mixtures of porphyrins from biological samples. 2. Application of this technique to urinary, faecal and hepatic porphyrins from patients with symptomatic porphyria revealed five porphyrins of interest which could be identified by mass spectrometry as the methyl esters of porphyrins with ...

Noncovalently functionalized Ti 3 C 2 T X MXenes are prepared via electrostatic interactions between cationic porphyrins and . Various spectroscopic microscopic techniques used to characterize the two hybrids, which show enhanced stability against oxidation a pH dependent release of porphyrins.

Porphyrins are known to be efficient photosensitizer molecules and the combined action of light and porphyrins in Propionibacterium acnes have a lethal action on the cells. Identification and quantification of in situ porphyrins in P. acnes have been done using an integrating sphere connected to an ordinary absorption spectrophotometer, and the amounts of porphyrins in the cells were quantified...

Functionalized asymmetric porphyrins bearing highly reactive centers in substituents at the mesopositions were synthesized in good yields by the reaction of 5,15-diphenylporphyrin with organolithium reagents. Using these porphyrins as precursors highly complex tetrapyrrolic systems are accessible. The synthetic strategy is based on our earlier reports on the combined use of organolithium and al...

Methods developed for porphyrin analysis have low recoveries and/or poor precision for the less polar protoporphyrin IX. We describe a simple method of analysis of porphyrins and biliverdin in bile and excreta of birds based on extraction with HCl 3N: acetonitrile and HPLC/UV analyses. Recoveries were good for protoporphyrin IX and other porphyrins (>79%). Applications of this method showed tha...

Porphyrias are a family of inherited diseases, each associated with a partial defect in one of the enzymes of the heme biosynthetic pathway. In six of the eight porphyrias described, the main clinical manifestation is skin photosensitivity brought about by the action of light on porphyrins, which are deposited in the upper epidermal layer of the skin. Porphyrins absorb light energy intensively ...

The inhibition of the corrosion of N80 steel in 3.5 wt. % NaCl solution saturated with CO2 by four porphyrins, namely 5,10,15,20-tetrakis(4-hydroxyphenyl)-21H,23H-porphyrin (HPTB), 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphyrin (T4PP), 4,4',4″,4‴-(porphyrin-5,10,15,20-tetrayl)tetrakis(benzoic acid) (THP) and 5,10,15,20-tetraphenyl-21H,23H-porphyrin (TPP) was studied using electrochemical impedan...