INTRODUCTION Rituximab has significantly improved the prognosis for patients with both indolent and aggressive non-Hodgkin's lymphoma. An economic evaluation was carried out to assess the cost-effectiveness in Sweden of rituximab as maintenance therapy for patients with follicular lymphoma in remission after second line therapy. MATERIALS AND METHODS The incremental cost and effectiveness of ...

The mental and physical capabilities of drivers in traffic are often seriously challenged these days. Not only do they need to concentrate on driving, predict connections between various phenomena, take appropriate judgements in current situations and foresee the sequence of measures to be taken, but they are also expected to be emotionally stable, etc. The problem with drugs in traffic is ofte...

Substance abuse is also related to psychological skills that affect the treatment process. Identifying the role of these skills can be useful for the development of a better intervention. This purpose of this study was to compare the coping strategies and emotion regulation profiles among opium users, methadone maintenance treatment clients, and normal individuals. The sample was selected among...

Maintenance chemotherapy has failed to demonstrate any benefit [1, 2]. Corticosteroid maintenance was found to prolong the duration of response; however, the effect on survival was controversial [3, 4]. Interferon-a represented a great hope in the 1980s but metaanalysis of randomized trials showed a modest increase in progression-free survival (PFS) and a minimal benefit in overall survival (OS...

Although most of the care received by bipolar patients occurs during the maintenance phase, relatively little empirical data is available to guide long-term treatment decisions. We review literature pertaining to key questions related to use of pharmacotherapy in the maintenance phase of bipolar disorder. The few double-blind trials with a reasonable sample size are restricted to bipolar I pati...

„ Switch maintenance treatment has been found to be an effective strategy in prolonging overall survival. The benefit in progression-free survival and overall survival, reported with pemetrexed in patients with nonsquamous histology and erlotinib in unselected patients as switch maintenance, and their favorable toxicity profile allow them to be used as maintenance treatment after induction ther...