نتایج جستجو برای: maintenance chemotherapy

تعداد نتایج: 257449  

Journal: :Blood 2006
Michel Attal Jean-Luc Harousseau Serge Leyvraz Chantal Doyen Cyrille Hulin Lofti Benboubker Ibrahim Yakoub Agha Jean-Henri Bourhis Laurent Garderet Brigitte Pegourie Charles Dumontet Marc Renaud Laurent Voillat Christian Berthou Gerald Marit Mathieu Monconduit Denis Caillot Bernard Grobois Herve Avet-Loiseau Philippe Moreau Thierry Facon

Newer chemotherapeutic protocols as well as high-dose chemotherapy have increased the response rate in myeloma. However, these treatments are not curative. Effective maintenance strategies are now required to prolong the duration of response. We conducted a randomized trial of maintenance treatment with thalidomide and pamidronate. Two months after high-dose therapy, 597 patients younger than a...

2017
Masao Ichiki Ken Masuda Chiyo Yano Yusuke Okayama Hanako Oda Yohei Imamura Hiroaki Takeoka Tomoaki Hoshino

The aim of this study is to determine the feasibility of nivolumab as maintenance therapy after first-line chemotherapy with carboplatin plus nab-paclitaxel in non-small-cell lung cancer. Since we cannot change the dose of nivolumab, we will investigate the recommended doses and cycles of pretreatment chemotherapy with carboplatin plus nab-paclitaxel that affect maintenance therapy. The primary...

Journal: :European review for medical and pharmacological sciences 2013
D Leopardo S C Cecere M Di Napoli C Cavaliere C Pisano S Striano L Marra L Menna L Claudio S Perdonà S Setola M Berretta R Franco R Tambaro S Pignata G Facchini

Non-Muscle-Invasive-Bladder-Cancer represents 75-85% of the new bladder cancer cases per year. Trans-uretral vesical resection is the milestone for diagnosis and therapy. After primary treatment, recurrence is frequent depending on the presence of several established risk factors: multiplicity, T dimension, prior recurrence. In some patients disease progress to an advanced stage. Adjuvant chemo...

2017
María Jesús Rubio Pérez

INTRODUCTION The current standard of care for ovarian cancer is optimal cytoreduction with adjuvant chemotherapy based on a platinum/taxane combination. Although the response rate to this therapy is high, most patients ultimately relapse. Response to second-line therapy and prognosis are linked to the platinum-free interval (PFI); when both improve, the PFI increases. As a result, there is an i...

Journal: :Acta medica Okayama 1979
I Kimura T Ohnoshi Y Nakata K Takasugi M Fujii K Hayashi M Kataoka M Sato R Nishihara

Clinical trials of immuno-chemotherapy were conducted on malignant lymphoma patients. Patients during the period from 1972 through 1977 were allocated to two groups retrospectively according to the mode of treatment, i.e., chemotherapy alone (historical control group, 35 patients) and chemotherapy with OK-432 (treated group, 15 patients). Comparisons were made of the two groups, which were homo...

Journal: :The Lancet 2016
Jonathan A Ledermann Andrew C Embleton Fharat Raja Timothy J Perren Gordon C Jayson Gordon J S Rustin Stan B Kaye Hal Hirte Elizabeth Eisenhauer Michelle Vaughan Michael Friedlander Antonio González-Martín Daniel Stark Elizabeth Clark Laura Farrelly Ann Marie Swart Adrian Cook Richard S Kaplan Mahesh K B Parmar

BACKGROUND Angiogenesis is a validated clinical target in advanced epithelial ovarian cancer. Cediranib is an oral antiangiogenic vascular endothelial growth factor receptor 1-3 inhibitor that has shown antitumour activity in recurrent ovarian cancer. We assessed efficacy and safety of cediranib in combination with platinum-based chemotherapy and as continued maintenance treatment in patients w...

2014
Li Xiang-Xin Wang Lu-Qun Li Hao He Xiao-Peng Li Fang-Lin Wang Ling-Ling Chen Xue-Liang Hou Ming

Objectives. To test the efficiency and safety of sequential application of retinoic acid (ATRA), Realgar-Indigo naturalis formula (RIF) and chemotherapy (CT) were used as the maintenance treatment in patients with acute promyelocytic leukemia (APL). Methods. This was a retrospective study of 98 patients with newly diagnosed APL who accepted two different maintenance treatments. After remission ...

Journal: :Interventional radiology 2023

We report two cases of liver metastases from colorectal and anal cancers after the failure systemic chemotherapies that were successfully treated with a combination therapy transarterial chemoembolization using irinotecan-loaded drug-eluting beads hepatic arterial infusion chemotherapy. In both cases, chemotherapy was performed as maintenance beads. Irinotecan at dose 120 mg loaded on drug deli...

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